What is alkaline phosphatase function?
What is alkaline phosphatase function?
What is alkaline phosphatase? ALP is an enzyme found in your bloodstream. It helps break down proteins in the body and exists in different forms, depending on where it originates. Your liver is one of the main sources of ALP, but some is also made in your bones, intestines, pancreas, and kidneys.
What is alkaline phosphatase a marker of?
An alkaline phosphatase (ALP) test measures the amount of ALP in your blood. Although ALP exists throughout your body, the two main sources of ALP in your blood are your liver and bones. High levels of ALP may indicate liver disease or certain bone disorders, but an ALP test alone cannot diagnose a condition.
What is unknown about alkaline phosphatase?
They often are associated with cell membranes, but their exact physiologic function is unknown. Despite this, alkaline phosphatase activity is a very useful serum biochemical indicator of liver disease, particularly cholestatic disease.
What is alkaline phosphatase PDF?
The alkaline phosphatase enzyme is an important serum parameter and its increase in serum is correlated with the presence of liver, bone, intestinal, renal and other diseases as it is divided into different isozymes. It functionally catalyzes the hydrolysis of phosphate monoesters at basic pH values (Sharma et al.
What is alkaline phosphatase Slideshare?
INTRODUCTION. TOPIC. LOCATION • ALP present in all tissues but it is particularly concentrated in liver, bile duct,kidney,bones,placenta,intestinal mucosa. CLINICAL SIGNIFICANCE OF ALP •ALP test is used to detect Liver disease,Bone disorders,biliary obstruction and cancer.
Where is alkaline phosphatase found?
An alkaline phosphatase (ALP) test measures the amount of ALP in your blood. ALP is an enzyme found throughout the body, but it is mostly found in the liver, bones, kidneys, and digestive system. When the liver is damaged, ALP may leak into the bloodstream.
Where is ALP secreted?
Alkaline phosphatase activity is present in the liver, bone, kidney, small intestine, and other organs of the body, and placenta in pregnancy. In sera of healthy adults, ALP activity originates mainly in the liver, with most of the rest coming from the skeleton.
Where is alkaline phosphatase produced?
What are alkaline phosphatase levels?
The normal range is 44 to 147 international units per liter (IU/L) or 0.73 to 2.45 microkatal per liter (µkat/L). Normal values may vary slightly from laboratory to laboratory. They also can vary with age and sex.
