What is ABO specific?
What is ABO specific?
All humans and many other primates can be typed for the ABO blood group. There are four principal types: A, B, AB, and O. There are two antigens and two antibodies that are mostly responsible for the ABO types. The specific combination of these four components determines an individual’s type in most cases.
What is an ABO antigen?
The ABO blood group antigens are attached to oligosaccharide chains that project above the RBC surface. These chains are attached to proteins and lipids that lie in the RBC membrane. Molecular basis. The ABO gene indirectly encodes the ABO blood group antigens. The ABO locus has three main allelic forms: A, B, and O.
What is the other name of blood group antigen?
The antigens expressed on the red blood cell determine an individual’s blood group. The main two blood groups are called ABO (with blood types A, B, AB, and O) and Rh (with Rh D-positive or Rh D-negative blood types).
What is the principle involved in the method of ABO typing?
ABO blood grouping is based on the principle of an agglutination reaction. It is the popular method for blood group identification to determine the presence and absence of cellular antigens and their relative antibodies in the blood.
What is the difference between ABO and Rh blood groups?
The main difference between ABO blood group and RH blood group is that ABO blood group is determined by the presence or absence of A and B antigens on the surface of the red blood cell whereas RH blood group is determined by the presence or absence of D antigen on the surface of the red blood cell.
What is the principle of ABO blood grouping?
Principle: The ABO and Rh blood grouping system is based on agglutination reaction. When red blood cells carrying one or both the antigens are exposed to the corresponding antibodies they interact with each other to form visible agglutination or clumping.
Where are the ABO antigens located?
Where are the ABO antigens located? They can be on red cells, lymphs, platelets, epithelial cells, endothelial cells and organs. The soluble antigens can be found in body fluids and secretions.
What is the specific term for the production of red blood cells?
As stated above, in adults the principal sites of red cell production, called erythropoiesis, are the marrow spaces of the vertebrae, ribs, breastbone, and pelvis. Within the bone marrow the red cell is derived from a primitive precursor, or erythroblast, a nucleated cell in which there is no hemoglobin.
Is ABO grouping your blood type?
ABO grouping is a test performed to determine an individual’s blood type.
What are the sources of error in ABO grouping?
Table 2
| Type of discrepancy | Causes of ABO discrepancy | Total N (%) |
|---|---|---|
| Technical/clerical errors | Blood donor identification error | 12(9.3) |
| Mislabeling of sample tubes | ||
| Forward blood grouping | Subgroup of A Antigen (n); A2 (31), A3 (7), A2B (20) | 61(46.9) |
| Subgroup of B Antigen (n); B3 (3) |
Are ABO antigens integral?
The antigens are an integral part of the red blood cell membrane. They lend stability to the membrane structure when they are normal, but result in decreased red cell survival when absent.
What are ABO and Rh antigens?
A person’s ABO type depends upon the presence or absence of two genes — the A and B genes. These genes determine part of the configuration of the red blood cell surface. Possible ABO blood groups include O, A, B, or AB. The Rh antigen is another compound that may or may not be present on the surface of red blood cells.
