What is a translational research team?

Translational Research takes scientific discoveries made in the laboratory, in the clinic or out in the field and transforms them into new treatments and approaches to medical care that improve the health of the population.*

What are the 3 types of translational research?

Translational Pipeline The schematic outlines/classifies the stages of translational research as: T1 – developing treatments and interventions. T2 – testing the efficacy and effectiveness of these treatments and interventions. T3 – dissemination and implementation research for system-wide change.

Who funds translational research?

In the United States, translational research is funded, in large part, by Clinical and Translational Science Awards (CTSAs), a program that is part of the Division of Clinical Innovation at the NIH National Center for Advancing Translational Sciences (NCATS).

What type of research is translational research?

Translational research seeks to produce more meaningful, applicable results that directly benefit human health. The goal of translational research is to translate (move) basic science discoveries more quickly and efficiently into practice.

What is the difference between translational and clinical research?

Clinical research is medical research that involves people like you. Translational research is research that applies discoveries generated in the laboratory to studies in humans (bench to bedside), or that speeds the adoption of best practices into community settings (bedside to practice).

What does a translational scientist do?

Translational scientists seek to understand the fundamental scientific and operational principles of each step of the translational process, with the goal of developing novel medical interventions that drastically improve their efficiency and efficacy.

What is translational research model?

Translational research is a dynamic continuum from basic research through application of research findings in practice, communities and public health settings to improve health and health outcomes. Translation Research progresses across five phases: Preclinical and animal studies (T0/Basic Science Research)

What is T1 T2 and T3 in translational research?

T1 involves processes that bring ideas from basic research through early testing in humans. T2 involves the establishment of effectiveness in humans and clinical guidelines. T3 primarily focuses on implementation and dissemination research while T4 focuses on outcomes and effectiveness in populations.

What is a CTSA NIH?

Under NCATS’ leadership, the Clinical and Translational Science Awards (CTSA) Program supports a national network of medical research institutions — called hubs ― that work together to improve the translational research process to get more treatments to more patients more quickly.

What is translational funding?

Translational funding is used to ‘bridge the gap’ in development between early stage technology resulting from university research and its commercialisation. The funding can help develop and support your opportunity by de-risking the project to potential commercial partners therefore making it more attractive.

What is an example of translational research?

One prime example of translational research in human disease is the study of cancer therapy. Extensive cooperation between basic researchers, clinicians, and industry has generated numerous new targeted compounds with enhanced efficacy and decreased toxicity.

What are the two areas of focus for translational research?

Translational research includes two areas of translation. One is the process of applying discoveries generated during research in the laboratory, and in preclinical studies, to the development of trials and studies in humans.