What is a high shear granulator?
What is a high shear granulator?
High shear granulation is a shaping process for granulation that has been enhanced for application in the pharmaceutical industry. A binder liquid is fed to the powder particles in a closed container with blending tools and a chopper. Dense granules are formed through the liquid and solid bridges that result.
Which granulation equipment is a high shear granulator with a chopper?
Rapid mixer granulator is used for granulation in pharmaceutical manufacturing. Impellers and choppers are responsible for uniform mixing and granule formation. Rapid mixer granulator is widely used equipment in pharmaceutical manufacturing.
What is high speed granulator?
A high-shear granulator or high-shear mixer uses a rotating impeller or high-speed rotor (or both) to create flow and shear. High-shear granulation is an effective way to turn powders into dense granules for tableting or coating.
What is shear granulation?
High shear wet granulation is a shaping process for granulation that has been successfully used by the pharmaceutical industry for decades. With high-shear granulation, a binding fluid is added to the powdery particles in a closed tank that has an agitator blade and chopper.
How does a high-shear mixer work?
A high-shear mixer uses a rotating impeller or high-speed rotor, or a series of such impellers or inline rotors, usually powered by an electric motor, to “work” the fluid, creating flow and shear.
What is low shear granulation?
Low shear granulation, which is a form of wet granulation, is an important unit operation in the pharmaceutical, detergent and food industries. The granulation mechanisms for wet granulation include wetting and nucleation, consolidation and growth and attrition and breakage.
What is ampere load in RMG?
What Is Ampere Load In RMG? Ampere load is the current which is used by the chopper and impeller for the rotation of powder or granules. Ampere load is high at the start of the process and then gradually decreases as the load on the motor decreases.
What is the function of a granulator?
Granulators are essentially rotary grinders that are used to grind scrap parts and melt delivery systems (sprues and runners) into feedstock sized granules for reprocessing. This allows the molder to reduce waste and produce components more cost effectively.
What mixers work with high shear stress?
There are four types of high shear mixers: batch, in-line, powder injection, and granulators. Batch and in-line high shear mixers are the two main types, while the other two are modifications. Batch high shear mixers can process large volumes in a shorter period.
Why is wet granulation used?
Wet granulation reduces the level of dust present during manufacturing process thereby reducing the incidence of cross-contamination and risk to workers. 9. Wet granulation reduces the amount of air entrapment thereby increasing powder compressibility.
What is Torque in RMG?
The magnitude of this torque is rmg sin θ, where θ is the angle between r and F. For the mass hangers, when the meter stick is horizontal, θ equals 90 degrees, sin θ equals 1, and τ = rmg. Torque, especially in this context, is often called the moment of force, and r is the moment arm.