What injection is given for priapism?

Intracavernous injection: This treatment is used for low-flow priapism. Drugs known as alpha-agonists are injected into the penis. They cause the arteries to narrow, reducing blood flow to the penis and causing the swelling to decrease.

Why is phenylephrine used for priapism?

Further, the risk of post-priapism ED is lower when sympathomimetic agents are used [Montague et al. 2003]. Phenylephrine is the preferred sympathomimetic agent because of its lower risk profile for systemic cardiovascular adverse effects than other agents [Burnett and Bivalacqua, 2007].

Why does sickle cell anemia cause priapism?

SCD causes priapism when sickled red blood cells block blood flow out of the penis. This blocks blood from circulating normally in the penis and leads to low oxygen levels, tense rigidity, and pain. Over time, this leads to permanent injury and inflammation, causing erectile dysfunction.

Does aspirin help with priapism?

Administer preoperative aspirin 325 mg orally and heparin 5000 units subcutaneously to prevent clotting of the shunt and recurrence of priapism. Close the skin incision with a running 5-0 Vicryl or chromic suture and observe for 15 minutes.

Where do you inject phenylephrine for priapism?

Draw 0.5 mg of phenylephrine into a 27 gauge (G) syringe. Place the needle into the corpus cavernosum on the selected side, close to the base of the penis at the two or ten o’clock position. Aspirate a little to confirm that you are in the corpus, and then inject the phenylephrine.

What is the drug papaverine used for?

Papaverine is used to produce erections in some men with erectile dysfunction. When papaverine is injected into the penis (intracavernosal), it increases blood flow to the penis, which results in an erection.

Is priapism common in sickle cell anemia?

Priapism (penile erection in the absence of sexual activity or desire) is a common complication and cause of morbidity in males with sickle cell disease (SCD) including children, adolescents, and adults.

What is hydroxyurea used for in sickle cell?

Hydroxyurea makes your red blood cells bigger. It helps them stay rounder and more flexible — and makes them less likely to turn into a sickle shape. The medicine does this by increasing a special kind of hemoglobin called hemoglobin F.

Where do you inject papaverine?

Using a sterile needle, inject the medicine slowly and directly into the base of the penis as instructed by your doctor. Papaverine should not be injected just under the skin. The injection is usually not painful, although you may feel some tingling in the tip of your penis.

What is cisapride used for?

Cisapride is used to treat symptoms of nighttime heartburn in people who have not responded to other treatments.