What factors determine the specificity of a signal response?

Factors that determine signal specificity in this system are poorly understood. Such factors include the relative affinity and stoichiometry of R-G or G-E and the possible colocalization of R-G-E in cellular microdomains.

What makes cell signaling a highly specific process?

Answer and Explanation: Cell signaling is specific because receptor proteins in cells attach to signaling molecules and trigger a physiological response.

What is signal specificity?

We defined the specificity of a pathway as the ratio of its authentic output to its spurious output, and the fidelity of a pathway as its output when given an authentic signal divided by its output in response to a spurious signal.

What does cell signaling depend on?

In order to detect a signal (that is, to be a target cell), a neighbor cell must have the right receptor for that signal. When a signaling molecule binds to its receptor, it alters the shape or activity of the receptor, triggering a change inside of the cell.

What determines the specificity of a receptor protein?

Receptor specificity depends on the binding affinity between the ligand and the binding site on the receptor. The dissociation constant (KD) describes the affinity between receptors and their ligands.

What causes the inactivation of Ag protein quizlet?

In the G protein-coupled signal transduction pathway, phosphatases are responsible for the inactivation of: All of these choices are correct.

What determines whether a cell is a target cell for a particular signal molecule?

A cell is a target cell if it has a receptor protein that recognizes the signal molecule.

How is it that different cells can respond in different ways to exactly the same signaling molecule even when they have identical receptors?

Explanation. Even though cells have identical receptors, cells are able to respond in different ways because they have types of machinery internally capable of coupling. They can respond differently because they are able to elicit different effector proteins in the pathways.

What cellular mechanism can increase the efficiency of a signal?

Amplifier proteins, which are usually either enzymes or ion channels, greatly increase the signal they receive, either by producing large amounts of small intracellular mediators or by activating large numbers of downstream intracellular signaling proteins.

How is signal efficiency accomplished in the cell?

How is specificity accomplished in cell signaling? Different cells can have different protein in then pathway replaced by another protein, creating different responses in different kinds of cells. Some cells may also use cross-over between two pathways to regulate the signal.

Which of the following are modes for cell signalling regulation?

The different types of cell signalling include:

  • Paracrine signalling.
  • Autocrine signalling.
  • Endocrine signalling.
  • Direct Contact.

What are the nature and importance of specificity in the binding of receptors to their particular ligands?

What is the nature and importance of specificity in the binding of a receptor to its particular ligand? Specificity ensures that only those cells that make a specific receptor will respond to a given Ligand signal.