What does x Chem do?

X-Chem offers services, products, and solutions that can help accelerate all aspects of drug discovery, from screen to candidate. Work with our industry-leading scientists to get the most our of our powerful technologies. At X-Chem, our mission is to help our clients get medicines to patients faster.

What is Del screening?

DNA-encoded library (DEL) screening, a modern iteration of combinatorial chemistry made possible by the invention of high-throughput DNA sequencing, has emerged as a robust tool for hit generation in the pharmaceutical industry.

How do DNA-encoded libraries work?

The most popular method for creating a DNA-encoded library involves assembling DNA and a small organic building block. These components are split into wells, and another building block is added, along with a second piece of identifying DNA.

What does relay therapeutics do?

Relay Therapeutics® is creating new possibilities in drug discovery. We aim to drug the undruggable. We are advancing a pipeline of promising therapeutic candidates, with an initial focus on precision oncology and genetic disease.

What is DNA-encoded library screening?

DNA-encoded library (DEL) technology is a novel ligand identification strategy that allows the synthesis and screening of unprecedented chemical diversity more efficiently than conventional methods.

What do you get from DNA-encoded libraries?

DNA-encoded libraries (DEL) technology is a game changing innovation in drug discovery. Conceptually designed by Brenner and Lerner1, DEL allows the synthesis and screening of millions, or even billions, of encoded compounds cheaper and quicker than using conventional methods2.

What does the information in DNA encode for?

DNA? provides instructions for making proteins? (as explained by the central dogma?). The sequence of the bases?, A, C, G and T, in DNA determines our unique genetic code and provides the instructions for producing molecules in the body. The cell reads the DNA code in groups of three bases.

How many employees does relay therapeutics have?

159 total
Company Description: Relay Therapeutics, Inc. is located in Cambridge, MA, United States and is part of the Pharmaceutical and Medicine Manufacturing Industry. Relay Therapeutics, Inc. has 159 total employees across all of its locations and generates $3.03 million in sales (USD).

Who founded relay Therapeutics?

Mark Murcko
Mark Murcko, Ph. D., Chief Scientific Officer and Co-Founder, Relay Therapeutics; Senior Lecturer, Massachusetts Institute of Technology (MIT) D. E. Shaw Research (David E. Shaw, Ph.

Is ADME and DMPK the same?

A critical piece in drug discovery and development is conducting DMPK (Drug Metabolism and Pharmacokinetics) studies, often referred to as ADMET (Absorption, Distribution, Metabolism, Elimination, Toxicity) studies.

What does the DMPK gene do?

The DMPK gene provides instructions for making a protein called myotonic dystrophy protein kinase. This protein appears to play an important role in muscle, heart, and brain cells.