What does gastric mucosa mean?

The inner surface of the stomach is lined by a mucous membrane known as the gastric mucosa. The mucosa is always covered by a layer of thick mucus that is secreted by tall columnar epithelial cells.

What is gastric mucosal abnormality?

Gastric epithelial dysplasia occurs when the cells of the stomach lining (called the mucosa) change and become abnormal. These abnormal cells may eventually become adenocarcinoma, the most common type of stomach cancer.

What causes damage to gastric mucosa?

Factors in upper intestinal content that can produce acute injury to the gastric mucosa include lysolecithin and the bile acids. Both damage the gastric mucosal barrier by increasing mucosal permeability. The secondary and deconjugated bile acids are more toxic in this regard than are the primary or conjugated ones.

Can gastric mucosa be healed?

Superficial injury of the gastric mucosa, such as occurs after ethanol or aspirin ingestion, is usually resurfaced in 1 or 2 h. This is accomplished by rapid migration of surface mucous cells to cover the defect, followed by a later increase in cellular proliferation to restore the pits to their original length.

How long can stomach inflammation last?

Acute gastritis usually lasts for a short period of time. In most cases, it resolves spontaneously within a few days or weeks once the inflammation has settled. In other cases, however, acute gastritis can lead to recurrent or long-term inflammation of the gastric mucosa, otherwise known as chronic gastritis.

What is mucosa mean?

(myoo-KOH-suh) The moist, inner lining of some organs and body cavities (such as the nose, mouth, lungs, and stomach). Glands in the mucosa make mucus (a thick, slippery fluid). Also called mucous membrane.

What does thickening of the stomach wall mean?

The gastric wall thickening is a diagnostic challenge for gastroenterologists and can be caused by a wide variety of benign and malignant disorders including lymphoma, adenocarcinoma, Menetriers’ disease, Crohn’s disease, peptic ulcer disease, sarcoidosis and tuberculosis.

Can mucosal damage be reversed?

Normally, however, the mucosa can repair or minimize this damage almost as soon as it occurs by a process of epithelial cell migration called restitution.

How do you treat gastric mucosa?

Treatment

  1. Antibiotic medications to kill H. pylori.
  2. Medications that block acid production and promote healing. Proton pump inhibitors reduce acid by blocking the action of the parts of cells that produce acid.
  3. Medications to reduce acid production.
  4. Medications that neutralize stomach acid.

How long does it take for gastric mucosa to heal?

While these treatments may help gastritis, injured stomach lining may take up to 12 weeks to heal.