What does FISH mean in medical terms?

FISH stands for fluorescence in situ hybridisation. It is a test that looks for gene changes in cells. Genes are made of DNA. They control everything the cell does, including when it grows and reproduces. FISH tests look for specific genes or parts of genes.

What is FISH test in cancer?

Commonly called FISH, fluorescence in situ hybridization is a laboratory-based test that helps build out the full picture of a cancer diagnosis by zooming in on the genetic material in the cell – known as chromosomes.

What is a FISH test in multiple myeloma?

FISH testing (fluorescence in situ hybridization) is a way of testing myeloma genetics in individual patients. It uses special fluorescent dyes that only attach to specific parts of chromosomes.

What is the difference between karyotyping and FISH?

While conventional karyotyping provides a comprehensive view of the genome, FISH can detect cryptic or submicroscopic genetic abnormalities and identify recurrent genetic abnormalities in nondividing cells.

When is FISH test done?

FISH testing is done on breast cancer tissue removed during biopsy to see if the cells have extra copies of the HER2 gene. Fluorescence in situ hybridization (FISH) is a test that “maps” the genetic material in a person’s cells. This test can be used to visualize specific genes or portions of genes.

What is a FISH test in urology?

Fluorescence in situ hybridization (FISH) analysis is an FDA-approved, urine-based marker that assists in diagnosis and surveillance of invasive urothelial cancer.

What does a normal FISH test mean?

Fluorescence in situ hybridization (FISH) is a test that “maps” the genetic material in human cells, including specific genes or portions of genes. Because a FISH test can detect genetic abnormalities associated with cancer, it’s useful for diagnosing some types of the disease.