What does ACP mean fatty acid synthesis?

Acyl carrier protein
Acyl carrier protein (ACP) transports the growing fatty acid chain between enzyme domains of fatty acid synthase (FAS) during biosynthesis. 1. Because FAS enzymes operate upon ACP-bound acyl groups, ACP must stabilize and transport the growing lipid chain.

What is the prosthetic group of ACP?

Phosphopantetheine
Phosphopantetheine, also known as 4′-phosphopantetheine, is a prosthetic group of several acyl carrier proteins including the acyl carrier proteins (ACP) of fatty acid synthases, ACPs of polyketide synthases, the peptidyl carrier proteins (PCP), as well as aryl carrier proteins (ArCP) of nonribosomal peptide …

What is ACP in malonyl ACP?

Abstract. High Resolution Image. Malonylation of an acyl carrier protein (ACP) by malonyl Coenzyme A-ACP transacylase (MCAT) is fundamental to bacterial fatty acid biosynthesis. Here, we report the structure of the Steptomyces coelicolor (Sc) fatty acid synthase (FAS) ACP and studies of its binding to MCAT.

What does ACP stand for in biochemistry?

The acyl carrier protein (ACP) is a cofactor of both fatty acid and polyketide biosynthesis machinery. It is one of the most abundant proteins in cells of E.

What is ACP biochemistry?

The acyl carrier protein (ACP) is a cofactor of both fatty acid and polyketide biosynthesis machinery. It is one of the most abundant proteins in cells of E. coli.

What is acyl carrier protein and how it is activated?

A soluble enzyme activity which catalyzes the synthesis of acyl-acyl carrier protein from acyl carrier proteins, a long chain fatty acid, and ATP has been demonstrated in E. coli. The reaction requires high concentrations of both Ca++ and Mg++ for activity, and cleaves ATP to AMP and PPi.

Which is true of the acyl carrier protein ACP?

Which is true of the acyl carrier protein (ACP)? It transports the fatty acid chain during oxidation and synthesis.

What is the function of Malonyl-CoA?

Malonyl-CoA has long been recognized as an important precursor of fatty acid biosynthesis in lipogenic tissues such as the liver and has an important role in regulating fatty acid oxidation in heart and skeletal muscle. Malonyl-CoA has also recently emerged as an important regulator of food intake and energy balance.