What chemotherapeutic agents are associated with commonly causing mucositis?
What chemotherapeutic agents are associated with commonly causing mucositis?
Certain chemotherapeutic agents such as methotrexate and etoposide may also be secreted in saliva, leading to increased risk of direct mucositis [20].
Is chemotherapy a destructive agent?
Chemotherapy damages the genes inside the nucleus of cells. Some drugs damage cells at the point of splitting. Some damage the cells while they’re making copies of all their genes before they split. Chemotherapy is much less likely to damage cells that are at rest, such as most normal cells.
What is chemotherapy induced stomatitis?
Stomatitis, also called oral mucositis, is swelling and redness of the lining of your mouth. It can cause painful sores that can make it hard for you to eat, drink, or swallow. It’s a common side effect of cancer treatments such as some chemotherapy and radiation.
What chemo causes stomatitis?
The chemotherapy drugs most likely to cause mouth sores include: Capecitabine (Xeloda) Cisplatin. Cytarabine (Depocyt)
What are the most serious toxic effects of chemotherapeutic agents?
Cardiovascular effects can be among the most serious adverse events resulting from chemotherapy, and can occur early or late during the treatment. Cardiotoxicity can be mild, consisting of blood pressure changes, to more severe, such as myocardial infarction and heart failure.
What is the mechanism of action of chemotherapeutic agents?
These drugs exert their effect by either blocking the enzymes required for DNA synthesis or becoming incorporated into DNA or RNA. By inhibiting the enzymes involved in DNA synthesis, they prevent mitosis because the DNA cannot duplicate itself.
What is the difference between mucositis and stomatitis?
Mucositis is painful inflammation or ulceration of the mucous membranes anywhere along the gastrointestinal tract. Stomatitis (oral mucositis) refers to inflammation and ulceration that occur in the mouth. Stomatitis can affect any of the structures in the mouth: cheeks, gums, tongue, throat, lips, and roof or floor.
What is the most common adverse effect of chemotherapy?
Tiredness (fatigue) is one of the most common side effects of chemotherapy. Many people having treatment feel tired a lot of the time or get tired very easily doing everyday tasks.
