What are the advantages of controlled drug delivery system?
What are the advantages of controlled drug delivery system?
Table 4
| Advantages of Controlled DDS | Disadvantages of Controlled DDS |
|---|---|
| Protection from metabolism by enzymes/chemicals | Uptake by RES reduces efficacy |
| Improved bioavailability | Poorer IVIVC |
| Low dosing frequency | Limited standards |
| Better patient compliance | Higher manufacturing cost |
What is the major objective of controlled drug delivery system?
The general design objective of a controlled release system is to fabricate a device capable of constant zero-order drug release over a prolonged time period. Besides the therapeutic advantages from less fluctuation in drug blood levels, reduced dosing frequency is a great benefit to patients.
Why is the use of controlled drug delivery system better than the conventional administration of drugs?
Compared with the direct administration of bare chemo-drugs, drug encapsulation in a carrier offers a number of advantages, such as protection from degradation in the bloodstream, better drug solubility, enhanced drug stability, targeted drug delivery, decreased toxic side effects and improved pharmacokinetic and …
Which of the following is a disadvantage of rate controlled drug delivery system?
DISADVANTAGES 1. Decreased systemic availability in comparison to immediate release conventional dosage forms. 2. Poor in vivo – in vitro correlation.
What is controlled drug delivery system?
A controlled drug delivery system is aimed at releasing the correct dose of a therapeutic directly in the desired zone and during the required period of time. This allows maximizing the efficacy of the therapeutic and minimizing the possible side effects.
What are the disadvantages of drug delivery systems?
On the other hand, apart from several advantages, drug delivery systems also have some disadvantages including: (1) some in vivo instability of active targeted and modified drug delivery systems can be existed, (2) immune reactions can be occurred against intravenous administered carrier systems, (3) requires highly …
Which of the following is an disadvantage of rate controlled drug delivery system?
What is the rationale behind design of controlled drug delivery systems?
The basic rationale of a controlled release drug delivery system is to optimize the biopharmaceutics, pharmacokinetics, and pharmacodynamics properties of a drug in such a way that its utility is maximized through reduction in side effects and cure or control of disease condition in the shortest possible time by using …
What are the advantages of controlled drug delivery systems CDDS compared to conventional drug delivery?
Compared to conventional dosage forms such delivery systems offer numerous advantages including improved efficacy, reduced toxicity, and improved patient compliance and convenience. All controlled release systems are developed to improve the therapeutic effectiveness of the drug.
What are some of the possible advantages of controlled release pills?
Sustained release Increased efficacy through improved patient compliance resulting from reduced dosage frequency compared to immediate-release drugs. Reduced local and systemic side effects due to the gradual-release of drug into the GI tract, which reduces peak plasma concentrations.
