What are examples of antisialagogue?

Antisialagogues are drugs or substances that decrease the flow rate of saliva and their effect is opposite to that of sialagogues….Classic antisialagogues include:

  • atropine,
  • opium,
  • alkalies,
  • belladonna,
  • hyoscyamus,
  • stramonium,
  • tobacco in excess,
  • all nauseous or insipid substances.

What is glycopyrrolate mechanism of action?

Mechanism Of Action Glycopyrrolate, like other anticholinergic (antimuscarinic) agents, inhibits the action of acetylcholine on structures innervated by postganglionic cholinergic nerves and on smooth muscles that respond to acetylcholine but lack cholinergic innervation.

What is glycopyrrolate used for?

Glycopyrrolate is used to treat peptic ulcers in adults. It is also used to treat chronic, severe drooling caused by certain neurologic disorders (eg, cerebral palsy) in children 3 to 16 years of age.

What is the indication of atropine?

Intravenous (IV) atropine indications include patients with hypersalivation, bronchial secretions, or bradycardia. Large doses and repeat doses may be required. Ingestions especially require higher doses (up to 20 mg). Titrate to effect by monitoring the patient’s ability to clear excess secretions.

What is the mechanism of atropine?

Mechanism Of Action Atropine competitively blocks the effects of acetylcholine, including excess acetylcholine due to organophosphorus poisoning, at muscarinic cholinergic receptors on smooth muscle, cardiac muscle, secretory gland cells, and in peripheral autonomic ganglia and the central nervous system.

What is another name for glycopyrrolate?

Glycopyrrolate is available under the following different brand names: Cuvposa, glycopyrronium, and Robinul.

What is the difference between atropine and glycopyrrolate?

Glycopyrrolate appears to be five to six times more potent than atropine in its antisialogogue effect and also exhibits a selective, though prolonged, effect on salivary secretion and sweat gland activity. It has minimal cardiovascular, ocular and central nervous system effects.

What are side effects of glycopyrrolate?

Side Effects

  • Body aches or pain.
  • decrease in the frequency of urination.
  • decrease in urine volume.
  • difficulty in passing urine (dribbling)
  • difficulty with breathing.
  • ear congestion.
  • feeling of warmth.
  • loss of voice.

What is the other name for glycopyrrolate?

Glycopyrrolate (Robinul) belongs to a group of medications known as anticholinergics (or antimuscarinics), which block acetylcholine, a chemical in our body. By blocking acetylcholine, glycopyrrolate (Robinul) lowers the amount of acid in your stomach and helps to relieve symptoms of stomach ulcers.

What is the action of atropine?

Atropine competitively blocks the effects of acetylcholine, including excess acetylcholine due to organophosphorus poisoning, at muscarinic cholinergic receptors on smooth muscle, cardiac muscle, secretory gland cells, and in peripheral autonomic ganglia and the central nervous system.

What is the side effect of atropine?

These include dryness of the mouth, blurred vision, dry eyes, photophobia, confusion, headache, dizziness, fatigue, tachycardia, palpitations, flushing, urinary hesitance or retention, constipation, abdominal pain, abdominal distention, nausea, vomiting, loss of libido, and impotency.