Is there a generic for entacapone?

FDA has approved Aurobindo’s entacapone tablets USP, 200 mg, the generic equivalent to Novartis’ Comtan tablets 200 mg.

Why is entacapone prescribed?

Entacapone is used in combination with levodopa/carbidopa to treat end-of-dose “wearing off” effect in patients with Parkinson’s disease, sometimes called shaking palsy. Parkinson’s disease is a disorder of the central nervous system (brain and spinal cord).

What does Comtan cost?

The cost for Comtan oral tablet 200 mg is around $822 for a supply of 100 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.

What is the generic name for Comtan?

GENERIC NAME: ENTACAPONE – ORAL (en-TACK-up-own)

Is levodopa same as entacapone?

The difference between this medicine and other levodopa treatments is that this medicine contains entacapone. Entacapone helps levodopa last longer by blocking a substance called COMT enzyme. This enzyme breaks down levodopa before it reaches the brain. When less levodopa is broken down, more is available to the brain.

What happens if you stop taking entacapone?

Stopping entacapone suddenly may make your Parkinson’s disease worse and could have other dangerous effects. Your doctor probably will decrease your dose gradually if necessary.

Can entacapone be cut in half?

Do not split, crush or chew Carbidopa, Levodopa and Entacapone Tablets. Administer only one tablet at each dosing interval.

How effective is entacapone?

At the end of the study, the mean daily dose of levodopa was significantly decreased from baseline (from 737 to 696 mg; P < 0.05). The patients’ global assessment indicated that 69% of patients improved when given entacapone and this proportion was maintained until the end of the study (64%).

What does entacapone do for Parkinson’s?

Entacapone is used together with carbidopa and levodopa to treat “wearing-off” symptoms of Parkinson’s disease, such as stiffness, tremors, muscle spasms, and poor muscle control.

Can entacapone be used alone?

Entacapone used alone will not treat symptoms of Parkinson’s disease. Entacapone can be taken with or without food. Taking the medicine with food may help prevent nausea, which is a common side effect of entacapone. Drink plenty of liquids while you are taking entacapone.