Is tetracycline acid stable?

We show that the stability of tetracycline in acidic solution is grater that its stability in alkaline solution. We found finally that these conditions differ in the effect on the stability of tetracycline, tetracycline in the alkaline solution is less stable than in acidic solution and other solutions.

What is the pH of tetracycline?

2.5–6.5
Tetracycline was effectively degraded at a broad initial pH range of 2.5–6.5.

Is tetracycline hydrophilic or hydrophobic?

hydrophilic
Although drugs associated with the multidrug-resistance phenotype are typically hydrophobic compounds, these data suggest that resistance to tetracycline, despite its hydrophilic nature, is mediated by P-glycoprotein in these cell lines.

Does tetracycline dissolve in water?

Ethanol
AlcoholAlkali hydroxide
Tetracycline/Soluble in

What is the purpose of Anhydrotetracycline?

The transcriptional inducer anhydrotetracycline (aTc) and the bacteriostatic antibiotic tetracycline (Tc) are commonly used in all fields of biology for control of transcription or translation.

Is tetracycline hydrochloride soluble in water?

Preparation Instruction This product is freely soluble in water, soluble in methanol and ethanol but insoluble in ether and hydrocarbons. (50 mg/ml) with heating, yielding a clear, yellow to yellow-orange solution. A clear, yellow green solution also results when 50 mg is dissolved in 4 ml 95% ethanol with heating.

Is tetracycline acidic or basic?

Tetracyclines are a group of broad-spectrum antibiotic compounds that have a common basic structure and are either isolated directly from several species of Streptomyces bacteria or produced semi-synthetically from those isolated compounds.

Does tetracycline degrade?

Degradation of tetracycline by the pure fungi and bacteria requires the addition of organic carbon source, but it can not be mineralized. The degradation cycle of tetracycline is relatively long by the microbial flora, biochemical treatment process, and advanced treatment system, as well as nutrients removal.

Is tetracycline hydrophilic or lipophilic?

Although drugs associated with the multidrug-resistance phenotype are typically hydrophobic compounds, these data suggest that resistance to tetracycline, despite its hydrophilic nature, is mediated by P-glycoprotein in these cell lines.

What is the resistance of tetracycline?

Resistance to tetracyclines is usually attributed to one or more of the following: the acquisition of mobile genetic elements carrying tetracycline-specific resistance genes, mutations within the ribosomal binding site, and/or chromosomal mutations leading to increased expression of intrinsic resistance mechanisms.

https://www.youtube.com/watch?v=dJIeNvhSW4o