Is nodular lymphocyte predominant Hodgkin lymphoma rare?

Nodular Lymphocyte Predominant Hodgkin Lymphoma (NLPHL) is a very rare subtype of Hodgkin lymphoma which accounts for around 5% of Hodgkin lymphoma cases each year. NLPHL is slower growing in nature to the more common subtypes of HL which are more aggressive (fast growing) in nature.

What lymphocytes are affected in Hodgkin’s lymphoma?

Classic Hodgkin lymphoma These cells are usually an abnormal type of B lymphocyte. Enlarged lymph nodes in people with cHL usually have a small number of Reed-Sternberg cells with a lot of normal immune cells around them. These other immune cells cause most of the swelling in the lymph nodes.

What does lymphocyte-predominant mean?

This page was updated on May 26, 2022. Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a rare type of lymphatic cancer. It occurs when lymphocytes, a type of white blood cell in your immune system, behave abnormally. Specifically, NLPHL occurs in B lymphocytes.

What indicates Hodgkin’s lymphoma?

Complete blood count (CBC). This test measures the number of blood cells in a sample, including red blood cells, white blood cells, and platelets. A low level of red blood cells, white blood cells or platelets may indicate that the lymphoma is present in the bone marrow and/or blood.

Is nodular lymphocyte predominant Hodgkin lymphoma curable?

Outlook. Treatment for NLPHL is very effective. Most people either go into complete remission (no sign of lymphoma on tests and scans), or have a long period without any symptoms. Although NLPHL can come back (relapse), treatment is usually successful.

Is nodular lymphocyte curable?

Nodular Lymphocyte-Predominant Hodgkin Lymphoma Prognosis The prognosis (outlook) of NLPHL is overall very good. Because NLPHL is slow growing and usually found at an early stage, effective treatments have an excellent chance to cure the disease.

Is nodular lymphocyte-predominant Hodgkin lymphoma curable?