Is chlorpheniramine soluble in water?
Is chlorpheniramine soluble in water?
Soluble in water (250 mg/mL) and ethanol (100 mg/mL).
How do you dilute chlorpheniramine?
Dilution of chlorphenamine injection with sodium chloride intravenous infusion (0.9% w/v) should facilitate preparation. For example, diluting 0.2 ml chlorphenamine injection to 2 ml with sodium chloride 0.9% injection produces a solution containing chlorphenamine 1 mg/ml.
Which form of chlorpheniramine is more potent?
Among the series 1-methyl-4-(pyridin-4-yl)-[1,2,4]triazolo[4,3-a] quinazolin-5(4H)-one (S5) was found to be the most active antihistaminic agent, which is more potent (72.85 % protection) than the reference standard chlorpheniramine maleate (70.09 %).
What is the melting point of chlorpheniramine?
130 – 135°C
Structure for T3D2989: Chlorpheniramine
| Property | Value |
|---|---|
| Melting Point | 130 – 135°C |
| Boiling Point | 142°C |
| Solubility | 5500 mg/L (at 37°C) |
| LogP | 3.38 |
Is Chlorphenamine an acid or base?
Chlorpheniramine Maleate is a halogenated amine. Amines are chemical bases, and they neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base.
How do you give chlorphenamine?
Adults: The usual dose of chlorphenamine injection for adults is 10mg to 20mg, but not more than 40mg should be given within a 24-hour period. The injection may be given by the subcutaneous, intramuscular or intravenous route.
Is chlorpheniramine acidic or basic?
Chlorpheniramine Maleate is a halogenated amine. Amines are chemical bases, and they neutralize acids to form salts plus water. These acid-base reactions are exothermic.
Can chlorpheniramine be crushed?
If using a sustained-release product, do not split or crush tablets. If using a long-acting capsule, you may empty the contents of the capsule over food, but do not allow the beads to dissolve before the pet eats the food.
