How much clorazepate Can I give my dog?

The typical dose range for clorazepate in dogs is 0.5 to 1 mg per pound (1 to 2 mg/kg) orally every 8 to 12 hours. It has been recommended that the sustained delivery formulation be dosed at 22.5 mg for large dogs, 11.5 mg for medium-sized dogs, and 5.75 mg for small dogs, given every 12 to 24 hours.

What is clorazepate 7.5 mg used for?

Clorazepate is used to relieve symptoms of anxiety and alcohol withdrawal. It is also used with other medicines to treat partial seizures. Clorazepate is a benzodiazepine.

What is the brand name for clorazepate?

Clorazepate, sold under the brand name Tranxene among others, is a benzodiazepine medication. It possesses anxiolytic, anticonvulsant, sedative, hypnotic, and skeletal muscle relaxant properties.

Is Xanax and clorazepate the same?

Clorazepate (Tranxene) and alprazolam (Xanax) are both benzodiazepines that can be used for anxiety. But there are some differences in how they work in your body. For example, clorazepate (Tranxene) stays in your body a lot longer compared with alprazolam (Xanax).

How long does clorazepate stay in a dog’s system?

Clorazepate – Clinical Pharmacology The serum half-life is about 2 days. The drug is metabolized in the liver and excreted primarily in the urine.

How long does clorazepate last?

Since orally administered clorazepate dipotassium is rapidly decarboxylated to form nordiazepam, there is essentially no circulating parent drug. Nordiazepam, the primary metabolite, quickly appears in the blood and is eliminated from the plasma with an apparent half-life of about 40 to 50 hours.

Is clorazepate fast acting?

Tranxene (clorazepate) is a fast acting option to control anxiety and alcohol withdrawal symptoms. It can be used to treat different types of seizures. Available in generic.

How much clorazepate is too much?

Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg per day.

Is clorazepate being discontinued?

Executive Summary. Abbott is discontinuing its promotion of Tranxene (clorazepate dipotassium) as “anxioselective” after a year-long debate with FDA about the appropriateness of the term.

What are the doses of clorazepate?

Adults—At first, 30 milligrams (mg), followed by 30 to 60 mg in divided doses. Your doctor will set up a schedule that will gradually adjust your dose until your symptoms improve. The dose is usually not more than 90 mg per day. Children—Use and dose must be determined by your doctor.

How long does clorazepate take to kick in?

The following is a simple breakdown of these differences: Tranxene is considered to have a rapid onset, and its effects usually take hold within 30-60 minutes. Xanax has an intermediate onset range, which means that it will typically take longer for this drug to take effect compared to Tranxene.

What does clorazepate do in dogs?

Clorazepate dipotassium (brand names: Tranxene-SD®, Gen-Xene®) is a benzodiazepine used to treat behavior disorders and seizures. Anxiety disorders and phobias are most often treated with this medication. Its use in cats and dogs to treat seizures and behavior disorders is ‘off label’ or ‘extra label’.