How is the whole blood separated into its components?

During a platelet donation, called Apheresis, your whole blood is removed into sterile tubing and satellite bags. A machine called a centrifuge spins your blood to separate your red blood cells, platelets and plasma. As the blood is separated, the heavier reds cells sink to the bottom and are given back to you.

What are the steps involved in preparing the blood components?

One cycle consists of-one ECV whole blood collection in kit bowl, centrifugation of bowl to separate components, collection of required component (platelets) in collection bag and finally return other constituents like red cells, leucocytes and plasma to donor. This cycle is repeated till therapeutic dose is attained.

What is plasma fractionation process?

Plasma fractionation is the downstream processing of plasma that has been harvested by donors. It breaks plasma into individual proteins, or plasma fractions. (It should be noted that this is different from whole blood fractionation, which means taking whole blood and breaking it into its four main parts.)

What are the components of whole blood?

Whole blood is made up of red blood cells, white blood cells and platelets, all of which are suspended in a liquid called plasma. Whole blood and each of it’s four components are all valuable tools in modern medicine.

Where do blood fractions come from?

Minor Blood Fractions A concentration of clotting factors derived from plasma, containing Factor VIII (protein), von Willebrand, Factor I (Fibrinogen), and other clotting factors.

What are fractionated blood products?

Blood component fractionation is based on centrifugation and flash-freezing technology. Whole blood is separated into red cells and platelet-rich plasma by slow centrifugation. High-speed centrifugation is then applied to the platelet-rich plasma to yield one unit of random donor platelets and one unit of FFP.

How do you separate FFP from whole blood?

Apheresis fresh frozen plasma (AFFP) is collected by an automated in-line process using apheresis machines that separate and extract plasma from cellular whole blood components by centrifugation. Plasma collected by apheresis is frozen within eight hours of collection and labelled as an AFFP unit.

What are blood fractions used for?

They are also used in medical glues to seal wounds and to stop bleeding after surgery. Cryoprecipitate – A mix of several plasma proteins that help blood clot in order to stop bleeding.

How are blood fractions obtained?

What are the 4 main components of blood?

It has four main components: plasma, red blood cells, white blood cells, and platelets. Blood has many different functions, including: transporting oxygen and nutrients to the lungs and tissues. forming blood clots to prevent excess blood loss.

What are major blood fractions?

Blood fractions are split into major and minor fractions. The 4 primary or major blood components include red blood cells, white blood cells, platelets and plasma. Fractionation of blood is typically done by centrifuging the blood in order for it to separate into different parts.