How do you administer Marquis?

DOSAGE: Administer MARQUIS at a dose of 15 mg/kg (6.81 mg/lb) body weight as a loading dose for the first dose only. The loading dose is followed by a maintenance dose of 5 mg/kg (2.27 mg/lb) body weight once daily for a period of 27 additional days.

What is Ponazuril Marquis used to treat in horses?

Ponazuril (brand names: Toltrazuril sulfone®, Marquis®, Ponalrestat®) is an antiprotozoal medication used to treat equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona. It may also be used to treat other protozoal parasites such as Toxoplasma spp, coccidia, and Neospora caninum.

What is Marquis paste used for?

Marquis® Paste is indicated for the treatment of equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona. Ponazuril, the active ingredient in Marquis, crosses the blood/brain barrier and reaches the central nervous system where it kills Sarcocystis neurona.

What does Marquis do for horses?

Marquis (ponazuril) is indicated as an aid in reducing the clinical severity of Equine Protozoal Myeloencephalitis (EPM) caused by Sarcocystis neurona in horses; it is expected that approximately two horses out of three will respond favourably to treatment.

How do you dilute Marquis?

Dilute one syringe of paste (127 grams at 150 mgs/gm., 120 ml volume) in 21 mls* of water results in a solution of 135 mgs/ml. This can be dosed at 1 ml/10 lbs (30 mgs/kg). The solution should be stored in a light proof container or amber bottle and thoroughly shaken or stirred before administration.

What is the best treatment for EPM?

There are two treatment options for EPM.

  • A six-month course of antibiotic (trimethoprim-sulfonamide) and antiprotozoal agent (pyrimethamine).
  • A 28-day course of antiprotozoal (ponazuril). Horses may need a second round of ponazuril in some cases. This is the only FDA-approved treatment for EPM.

How often do you give ponazuril?

Instead, Dr. Cannon told the audience, “Results support use of oral ponazuril at 50mg/kg once every 24 hours for three consecutive days for treatment of coccidiosis with follow up fecal flotation. If still infected, treatment should be repeated.”

Is ponazuril a dewormer?

Ponazuril (Marquis Paste) is effective against coccidia. It is also very safe, even in kittens as young as 2 weeks. Marquis can be given on intake as a prophylactic single-dose treatment, followed with another dose a week later.

Who makes Marquis paste for horses?

Boehringer Ingelheim
Marquis from Boehringer Ingelheim is designated for the treatment of Equine Protozoal Myeloencephalitis (EPM) caused by Sarcocystis neurons. Marquis Paste is supplied in a ready-to-use syringe that contains 127 grams of paste. Each gram of paste contains 150 mg of ponazuril (15% w/w).

How do you treat coccidia?

The only Food and Drug Administration-approved treatment for coccidia is sulfadimethoxine, which must be prescribed by a veterinarian. There are other drugs that are used with some success in the treatment of coccidia, such as ponazuril, which has shown to be effective from the most current published research.

Does panacur treat coccidia?

Treating a Coccidia or Giardia Infection Although there are no FDA-approved treatments for canine giardiasis, most veterinarians use metronidazole (Flagyl) for five to seven days, and/or fenbendazole (Panacur) for three to five days, and then re-test.

What should I feed my horse with EPM?

We routinely recommend use of Essential K® or Wholesome Blends™ Balancer to support horses during EPM recovery because both products are highly concentrated in vitamins, minerals and the high-quality amino acids needed for muscle rebuilding.