How accurate is the Western Blot test for herpes?

Results. HSV-2 and HSV-1 seroprevalence by Western Blot were 3.4% and 48%, respectively. In this population, the positive predictive value of the Focus HSV-2 ELISA was 37.5%, the sensitivity was 100%, and specificity was 94.1%.

Can you falsely test negative for herpes?

Beyond 48 hours of the symptoms appearing, there is a risk of receiving a false negative test result. Viral culture is even less accurate during recurrences (positive in only about 30% of recurrent outbreaks).

Can a PCR test be false negative herpes?

Conclusion: CSF PCR for herpes virus is highly sensitive and specific and remains the standard for diagnosing herpes encephalitis. Clinicians should be aware of the pitfalls of CSF PCR testing, specifically false-negative results. Although rare, these false negatives can result in premature termination of treatment.

What can cause a false negative herpes test?

Fluid from a fresh sore is added to certain cells used to grow HSV. If no virus infects the cells, the culture is negative. If the herpes virus infects the cells, the culture is positive. The culture often fails to find the virus even when it is present (false-negative results).

What test is most accurate for herpes?

PCR test: The PCR test can tell if you have genital herpes even if you don’t have symptoms. The PCR test looks for pieces of the virus’s DNA in a sample taken from cells or fluids from a genital sore or the urinary tract. This is a commonly used test to diagnose genital herpes and is very accurate.

How accurate is a PCR blood test for herpes?

PCR assays or other NAATs are the most sensitive test currently available to detect HSV in clinical samples. The detection rates of the PCR assays were shown to be 11–71% superior to virus culture [26,41-44].

How accurate are PCR tests for herpes?

What is the most accurate herpes test?

What can herpes be misdiagnosed for?

While estimates predict that around 80% of those people experience little to no symptoms when symptoms do appear [2], they can sometimes be mistaken for other conditions, including: Chlamydia. Trichomoniasis. Syphilis.