Does Klippel-Trenaunay syndrome get worse with age?

In people with Klippel-Trenaunay syndrome, the port-wine stain usually covers part of one limb. The affected area may become lighter or darker with age.

Is Klippel-Trenaunay life threatening?

Klippel-Trenaunay syndrome (KTS) is a rare congenital syndrome of vascular malformations and soft tissue and bone hypertrophy. Vascular malformations can affect multiple organ systems. Involvement of the gastrointestinal (GI) tract is uncommon in KTS, but it can be a source of life-threatening bleeding.

Are KTS curable?

There is no cure for KTS. Treatment is symptomatic. Laser surgery can diminish or erase some skin lesions. Surgery may correct discrepancies in limb size, but orthopedic devices may be more appropriate.

How do you treat KTS?

Although there’s no cure for KTS , your doctor can help you manage symptoms and prevent complications….Treatments may include:

  1. Compression therapy.
  2. Skin care.
  3. Physical therapy.
  4. Orthopedic devices.
  5. Epiphysiodesis (ep-ih-fiz-e-OD-uh-sis).
  6. Embolization.
  7. Laser therapy.
  8. Laser or radiofrequency ablation of veins.

Are KTS painful?

Symptoms and severity of KTS vary for each patient. Symptoms can include bleeding from the affected limb, a skin infection, blood in the urine, or rectal/vaginal bleeding. You could experience pain in the limb, blood clots, anemia and seizures.

How common is KTS?

General Discussion. Klippel-Trenaunay syndrome (KTS) is a rare disorder that is present at birth (congenital) and is characterized by a triad of cutaneous capillary malformation (“port-wine stain”), lymphatic anomalies, and abnormal veins in association with variable overgrowth of soft tissue and bone.

What is a KTS leg?

Klippel-Trenaunay syndrome (KTS) is a rare congenital vascular disorder in which a limb may be affected by port wine stains (red-purple birthmarks involving blood vessels), varicose veins, and/or too much bone and soft tissue growth. The limb may be larger, longer, and/or warmer than normal.

What causes KTS syndrome?

KTS is a genetic disorder. It involves genetic changes (mutations), most commonly in the PIK3CA gene. This gene is responsible for the growth of cells and the development of tissues in the body.