What does the sigma-1 receptor do?
What does the sigma-1 receptor do? Sigma-1 receptor is a promising therapeutic target in the treatment of neurodegenerative diseases as it stabilizes the function of several intracellular systems through its role as a chaperone when activated by a variety of ligands with neuroprotective properties. What are sigma ligands? Sigma receptors (σ-receptors) are protein cell surface […]
What does the BEST1 gene do?
What does the BEST1 gene do? The BEST1 gene provides instructions for making a protein called bestrophin-1, which appears to play a critical role in normal vision. Bestrophin-1 is found in a thin layer of cells at the back of the eye called the retinal pigment epithelium. What is autosomal recessive Bestrophinopathy? Disease definition. A […]
Why is prasugrel discontinued?
Why is prasugrel discontinued? prasugrel has been discontinued in several countries because of low prescription rates.” Is Plavix as good as prasugrel? Several studies have compared the platelet inhibitory capacity of prasugrel and clopidogrel. Preclinical studies indicate that prasugrel is approximately 10-fold more potent than clopidogrel at inhibiting platelet aggregation, inhibiting thrombus formation, and prolonging […]
Is enzootic bovine leukosis notifiable?
Is enzootic bovine leukosis notifiable? Enzootic bovine leukosis is a notifiable animal disease. If you suspect it you must report it immediately by calling the Defra Rural Services Helpline on 03000 200 301. What is enzootic bovine leukosis? Enzootic bovine leukosis (EBL) is a viral disease that affects cattle, characterized by persistent lymphocytosis or lymphosarcoma […]
Does the Queen have any power in Australia?
Does the Queen have any power in Australia? Australia is a constitutional monarchy and our head of state is the Queen. However, the Queen does not have a role in the day-to-day running of Australia. On the advice of the Prime Minister, the Queen appoints the Governor-General, who is the Queen’s representative in Australia. Is […]
What is a B8 stud?
What is a B8 stud? Grade B8 stud bolts are made of AISI 304 stainless steel. These type of fasteners are made with austenitic stainless steel and require carbide solution treatment. What grade is a B8 bolt? ASTM A193 Grade B8 Raw Material Grade Tensile Class Raw Material Description B8 Class 1 AISI 304 Stainless […]
How do I customize my Visual Studio theme?
How do I customize my Visual Studio theme? Here’s how to change the color theme of the IDE frame and the tool windows in Visual Studio. On the menu bar, choose Tools > Options. In the options list, choose Environment > General. In the Color theme list, choose either the default Dark theme, the Light […]
How do I get the news on my tablet?
How do I get the news on my tablet? Add the Google News app widget On your Android device, touch and hold the Home screen. Tap Widgets . Touch and hold the Google News widget. Images of your Home screens appear. Slide the widget to where you want it and lift your finger. Which is […]
What is US DOE funding?
What is US DOE funding? The U.S. Department of Energy (DOE) SBIR/STTR programs provide grant opportunities to small businesses performing R&D in support of the DOE mission. Grants are competitively awarded for the development and commercialization of new ideas and innovative research. What is the difference between RFA and RFP? government grants (RFA). An RFP […]
Is Coogi still in style?
Is Coogi still in style? Coogi relaunched in 2014 with a focus on the authentic sweater for men, introducing new products and color treatments. According to The New York Times, the label is experiencing a resurgence. Fashion brands such as Rag & Bone, Pigalle, Burton and Supreme have been paying homage to Coogi. What does […]
What is Nonaka and Takeuchi model?
What is Nonaka and Takeuchi model? The Nonaka and Takeuchi model is one of the knowledge management model that can be used in the knowledge creation and conversion. Knowledge management models itself are the approach to manage knowledge from people and process of an organization. What is knowledge Nonaka? Nonaka and Takeuchi (1995) suggested that […]
Is The Man in the Iron Mask appropriate?
Is The Man in the Iron Mask appropriate? Parents need to know that this Three Musketeers adventure film based on the classic novel by Alexandre Dumas includes some fairly overt sexual references (but little nudity) and violence (but little blood). What is the plot of the movie The Man in the Iron Mask? The former […]