What does the sigma-1 receptor do? Sigma-1 receptor is a promising therapeutic target in the treatment of neurodegenerative diseases as it stabilizes the function of several intracellular systems through its role as a chaperone when activated by a variety of ligands with neuroprotective properties. What are sigma ligands? Sigma receptors (σ-receptors) are protein cell surface […]
Why is prasugrel discontinued? prasugrel has been discontinued in several countries because of low prescription rates.” Is Plavix as good as prasugrel? Several studies have compared the platelet inhibitory capacity of prasugrel and clopidogrel. Preclinical studies indicate that prasugrel is approximately 10-fold more potent than clopidogrel at inhibiting platelet aggregation, inhibiting thrombus formation, and prolonging […]
Is enzootic bovine leukosis notifiable? Enzootic bovine leukosis is a notifiable animal disease. If you suspect it you must report it immediately by calling the Defra Rural Services Helpline on 03000 200 301. What is enzootic bovine leukosis? Enzootic bovine leukosis (EBL) is a viral disease that affects cattle, characterized by persistent lymphocytosis or lymphosarcoma […]
How do I get the news on my tablet? Add the Google News app widget On your Android device, touch and hold the Home screen. Tap Widgets . Touch and hold the Google News widget. Images of your Home screens appear. Slide the widget to where you want it and lift your finger. Which is […]
Does the Queen have any power in Australia? Australia is a constitutional monarchy and our head of state is the Queen. However, the Queen does not have a role in the day-to-day running of Australia. On the advice of the Prime Minister, the Queen appoints the Governor-General, who is the Queen’s representative in Australia. Is […]
What is a B8 stud? Grade B8 stud bolts are made of AISI 304 stainless steel. These type of fasteners are made with austenitic stainless steel and require carbide solution treatment. What grade is a B8 bolt? ASTM A193 Grade B8 Raw Material Grade Tensile Class Raw Material Description B8 Class 1 AISI 304 Stainless […]
How do I customize my Visual Studio theme? Here’s how to change the color theme of the IDE frame and the tool windows in Visual Studio. On the menu bar, choose Tools > Options. In the options list, choose Environment > General. In the Color theme list, choose either the default Dark theme, the Light […]
What is the correct order to bleed brakes? The sequence is as follows: right rear, left rear, right front, left front. See all 10 photos When bleeding brakes, it’s important not to force the brake pedal down more than halfway. This runs the risk of driving the master cylinder’s secondary piston through debris collected on […]
What LED strips are best? These are the best LED light strips for every kind of setup, from little luminary boosts to full-on glow-ups. Best overall: Govee Smart LED Strip Lights. Best premium: Philips Hue Bluetooth Lightstrip. Best for rooms: Daybetter LED Strip Lights. Best for cars: Govee Interior Lights for Car. How long do […]
What did people do before there were supermarkets? Before supermarkets became a one-stop-shop, people shopped at separate, small stores for each category of food. A street would be lined with “greengrocers” (for produce), dairy shops, butchers, fishmongers and grocers that exclusively sold dry, packaged goods like canned food. When did people start going to grocery […]
What do P techs do? P–TECH is a public-education model that provides high school students from underserved backgrounds with the academic, technical, and professional skills and credentials they need for competitive STEM jobs. What does the P in P-tech stand for? Public-Private Partnership Public-Private Partnership A P-TECH school relies on developing and sustaining healthy partnerships […]
What is the last mile marker on the Blue Ridge Parkway? Mile 0 – Rockfish Gap near Waynesboro, Va., is the northern end of the Blue Ridge Parkway. What mile marker is the highest point on the Blue Ridge Parkway? Milepost 431 The highest elevation along the parkway road is 6,053 feet at Richland Balsam […]