Can nodal marginal zone lymphoma be cured?

Most patients with nodal marginal zone lymphoma present with advanced stage disease and are not likely to achieve cure, even with aggressive chemotherapy regimens. Moreover, there is little evidence that choice of initial therapy has any impact on survival.

How many people have marginal zone lymphoma?

Of the extranodal sites, the most common is stomach/gastric (GALT lymphoma) followed by ocular/adnexal, lung, skin, and salivary gland, the median age of a MZL diagnosis is 67 years and is slightly more common in men. It is estimated that there are 1000 to 2300 cases per year in the US.

What is marginal zone lymphoma?

Marginal zone lymphomas are types of slow-growing (low-grade) non-Hodgkin lymphomas that develop from B cells. They are called marginal zone lymphomas because they develop in a particular region found at the edge of normal lymphoid tissues (collections of lymphocytes) called the marginal zone.

What is Stage 4 marginal zone lymphoma?

Stage 4 lymphoma occurs when cancer has spread to a distant part of the body outside of the lymphatic system, such as the spinal cord, lungs, or liver. Lymphoma is cancer that originates in a type of white blood cell called lymphocytes.

What is marginal zone in lymph node?

The marginal zone is the region at the interface between the non-lymphoid red pulp and the lymphoid white-pulp of the spleen. (Some sources consider it to be the part of red pulp which borders on the white pulp, while other sources consider it to be neither red pulp nor white pulp.)

What is the treatment for marginal zone lymphoma?

Treatments Nodal MZL When treatment is necessary, options include radiation therapy, chemotherapy and/or immunotherapy, and other treatments commonly used in other types of slow-growing lymphomas, such as follicular lymphoma.

What are the symptoms of marginal zone lymphoma?

You may also have symptoms specific to the type of lymphoma. For example, people with MALT may experience: indigestion. stomach pain….Symptoms associated with all forms of the disease include:

  • fever without an infection.
  • night sweats.
  • unexplained weight loss.
  • skin rash.
  • chest or abdominal pain.
  • tiredness.