Can monoclonal antibodies deliver drugs to specific targets?

Monoclonal antibodies generated against specific antigens, when conjugated to cytotoxic drugs, can selectively deliver drugs to cancer cells while minimizing damage to normal cells.

What is a targeted monoclonal antibody?

Monoclonal antibodies (MABs) are a type of targeted drug therapy. These drugs recognise and find specific proteins on cancer cells. There are many different MABs to treat cancer. They work in different ways to kill the cancer cell or stop it from growing.

How are monoclonal antibodies delivered?

Monoclonal antibodies are administered through a vein (intravenously). How often you undergo monoclonal antibody treatment depends on your cancer and the drug you’re receiving. Some monoclonal antibody drugs may be used in combination with other treatments, such as chemotherapy or hormone therapy.

What are target antigen drugs?

Special drugs have been designed that identify and attack cells that have a particular type of CD antigens. These drugs are called monoclonal antibodies and they can attack only the type of cell that contains the specific target CD antigens.

What are targeted antibodies?

Targeted antibodies are a form of cancer immunotherapy treatment that can disrupt cancer cell activity and alert the immune system to target and eliminate cancer cells.

How does a monoclonal antibody work?

To make monoclonal antibodies, scientists expose a specific type of cell from the immune system to a particular viral protein — in this case, SARS-CoV-2, the virus that causes COVID-19. They can then design the mAb to target a particular virus or a specific part of the infection process.

What are the two most common delivery methods for antibody therapeutics?

Therapeutic biologicals, including mAbs, are commonly intravenously (IV) administered in hospital settings, but other routes such as subcutaneous or aerosol delivery could be preferred for some applications.

How are monoclonal antibodies used?

Monoclonal antibodies are used for diagnosis, disease treatment and research. They’re used: As probes to identify materials in laboratories or for use in home-testing kits like those for pregnancy or ovulation. To type tissue and blood for use in transplants.