Can measles cause giant cell pneumonia?

Can measles cause giant cell pneumonia?

In two fatal cases of measles the major pathologic finding was a pneumonia characterized principally by giant cells and inclusion bodies.

What virus causes giant cell pneumonia?

Giant cell pneumonia due to respiratory syncytial virus. Occurrence in severe combined immunodeficiency syndrome.

What causes giant cell pneumonia?

Giant cell pneumonia: A deadly but fortunately rare complication of measles that tends to strike children who are immunodeficient from leukemia or AIDS. The lung tissue shows multinucleated giant cells lining the alveoli (air sacs) of the lungs. Also known as Hecht’s pneumonia.

What causes pneumonia in measles?

Pneumonia may be caused by the measles virus alone, secondary viral infection with adenovirus or HSV, or secondary bacterial infection.

Why is pneumonia a complication of measles?

Abstract. Measles pneumonia is the most frequent complications associated with mortality in this infection. There are two types, one corresponds to the giant-cells pneumonia and the other one to lung superinfection after measles infection. The first one has been occurred in immunosuppressed patients, without rash.

How does RSV spread cell to cell?

Infection. RSV most often begins as an infection in the nasal epithelial cells. The G protein initiates attachment of the virus to the epithelial cell. The F protein is cleaved by proteolytic enzymes of the infected cell and the virus then fuses with the epithelial cell membrane and enters the cytoplasm.

What is cobalt lung?

The disease, called hard-metal pneumoconiosis or “cobalt lung,” usually occurs when people inhale mineral dusts caused by metal grinding, said senior researcher Dr. Kirk Jones, a pathologist with the University of California, San Francisco.

What is measles pneumonia?

Measles pneumonia is the most frequent complications associated with mortality in this infection. There are two types, one corresponds to the giant-cells pneumonia and the other one to lung superinfection after measles infection. The first one has been occurred in immunosuppressed patients, without rash.

What does measles do to the lungs?

Measles can commonly cause an infection in the lungs (pneumonia). People with weakened immune systems can develop an especially dangerous type of pneumonia that sometimes can lead to death. Encephalitis.

How does measles affect the respiratory system?

The respiratory and intestinal tracts are the most affected sites in measles-infected children. When the measles virus affects the lower respiratory tract epithelium and destroys local immunity within the lungs, an individual suffers from pneumonia [2,3].

What causes giant cell?

The cause of giant cell arteritis is still unknown but is thought to be from the immune system causing damage to the body’s own blood vessels. Polymyalgia rheumatica is an inflammatory disorder that is closely related to giant cell arteritis and occurs in 40% to 60% of patients with giant call arteritis.