Can I breastfeed on propylthiouracil?

Little PTU passes into breastmilk and infant thyroid suppression does not occur with usual maternal dosages. The American Thyroid Association[5] and others[6] state that it is safe for nursing mothers to use propylthiouracil in dosages up to 300 mg daily in divided doses.

Is Carbimazole safe in breastfeeding?

It’s usually OK to take carbimazole while you are breastfeeding. Carbimazole passes into breast milk but only in small amounts. This is probably too little to affect your baby. After a while, your doctor may take a blood test for the baby to check the levels of their thyroid hormones.

Can a breastfeeding mother take rifampicin?

Summary of Use during Lactation The Centers for Disease Control and Prevention and other professional organizations state that breastfeeding should not be discouraged in women taking rifampin. [1-3] Breastmilk may be stained a yellow, orange, red or brown color.

What is lactation category L3?

†— Lactation risk categories are as follows: L1 = safest; L2 = safer; L3 = moderately safe; L4 = possibly hazardous; L5 = contraindicated.

Which antithyroid drug is safe in breastfeeding?

The aim of this communication is to provide information regarding the use of antithyroid drugs (ATD) during lactation. Three ATD are used today: propylthiouracil (PTU), methimazole (MMI) and carbimazole (CMZ). The latter is a prodrug which is bioactivated to MMI. PTU is transferred in small amounts (0.025%) into milk.

Can you breastfeed with hyperthyroidism?

High thyroid levels (hyperthyroid) Hyperthyroidism is not a contraindication for breastfeeding. Per Medications and Mothers’ Milk (Hale 2017, p. 558-559, 564-565), only exceedingly low levels of thyroid hormones (both T4/levothyroxine and T3/liothyronine) transfer into breastmilk.

Is thyroid medication safe while breastfeeding?

It is generally safe to breastfeed while taking antithyroid drugs to treat an overactive thyroid (hyperthyroidism) provided the dose is low but you should check with your endocrinologist. Antithyroid drugs are best taken in smaller doses over two or three times a day following a feed.

Which drugs are contraindicated during breastfeeding?

Drugs contraindicated during breastfeeding include anticancer drugs, lithium, oral retinoids, iodine, amiodarone and gold salts. An understanding of the principles underlying the transfer into breast milk is important, as is an awareness of the potential adverse effects on the infant.

Is pyrazinamide safe for breastfeeding?

Pyrazinamide Breastfeeding Warnings Caution is recommended; benefit to mother should outweigh risk to the infant. -Some experts recommend: A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.

What are the pregnancy risk categories?

FDA Pregnancy Categories

  • Category A. Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
  • Category B.
  • Category C.
  • Category D.
  • Category X.

Which antithyroid drug is contraindicated in pregnancy?

Radioiodine therapy is contraindicated during preg- nancy and lactation. During the post partum period, all antithyroid drugs could be administered in nursing mothers, but MMI should be the drug of choice because of the risk of potential hepatotoxicity of PTU in either mother or child.

Can you breastfeed on thyroid medication?