Can cocaine cause troponin levels to rise?

Outside of reports addressing acute MI, this is the first study of which we are aware to report significantly higher troponin concentrations in cocaine-using patients compared to patients who do not use cocaine.

Why was levamisole taken off the market?

Levamisole was withdrawn from the American market in 2000 due to its ability to cause serious adverse effects, including agranulocytosis. Interestingly, levamisole has been found as an adulterant in cocaine and can lead to a variety of adverse effects in individuals using this drug.

Can Coke make your heart hurt?

Stimulants like cocaine have wide-reaching effects on the heart and blood vessels. According to the American Heart Association, chronic cocaine users are more likely to get high blood pressure, heart muscle wall thickening, and stiff arteries — all major risk factors for heart attacks.

How is levamisole poisoning treated?

Laboratory findings include neutropenia, positive perinuclear or cytoplasmic staining patterns for antineutrophil cytoplasmic antibodies, and positive antihuman elastase antibody. Treatment of levamisole toxicity is primarily supportive, and skin lesions typically resolve with cessation of cocaine use.

What drugs increase troponin levels?

Tocolytic drugs Fenoterol and Verapamil increased troponin level in a prospective cohort study of 22 women. Thirty-two percent and 40% of women had troponin elevation at day 1 and day 3 of treatment, respectively [54].

What are the troponin levels?

For example, the normal range for troponin I is between 0 and 0.04 ng/mL but for high-sensitivity cardiac troponin (hs-cTn) normal values are below 14ng/L. Other types of heart injury may cause a rise in troponin levels.

What is the brand name for levamisole?

Levamisole, sold under the brand name Ergamisol among others, is a medication used to treat parasitic worm infections, specifically ascariasis and hookworm infections. It is taken by mouth.

What is Phenyltetrahydroimidazothiazole?

ABSTRACT: Phenyltetrahydroimidazothiazole (i.e., levamisole, dexamisole, or tetramisole) has been increasingly utilized as a cutting agent by South American illicit cocaine laboratories for the past eight years, and is now the most predominant adulterant in cocaine produced in Colombia.