What is platinum chemotherapy?

Abstract. The platinum-based drugs cisplatin, carboplatin and oxaliplatin are regularly prescribed in the treatment of cancer and while they are effective, their use is limited by their severe, dose-limiting side effects (also referred to as adverse effects/events).

What does CIS mean in cisplatin?

Molecular structure. Cisplatin is the square planar coordination complex cis-[Pt(NH3)2Cl2]. The prefix cis indicates the cis isomer in which two similar ligands are in adjacent positions.

Is CIS Platin used in cancer chemotherapy?

Cisplatin, cisplatinum, or cis-diamminedichloroplatinum (II), is a well-known chemotherapeutic drug. It has been used for treatment of numerous human cancers including bladder, head and neck, lung, ovarian, and testicular cancers.

What is cisplatin platinum?

Cisplatin is a platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors.

What is GEM CIS chemotherapy?

What is GEM/CIS? Gemcitabine and cisplatin are two chemotherapy drugs which kill tumour cells by interfering with the process of cell replication. However, because they can also damage normal cells, they can cause some side effects.

How will I feel after cisplatin?

This medicine often causes nausea and vomiting. However, it is very important that you continue to receive this medicine even if you begin to feel ill. Other medicines may be given to you to help with the nausea and vomiting. Ask your doctor for other ways to lessen these effects.

Is CIS Platin still used?

Cisplatin has been used as a treatment for cancer since its approval by the US Food and Drug Administration in 1978. And while five other platinum drugs based on the structure of cisplatin have been developed since, it has never been replaced. Platinum drugs are now used in 40% of all chemotherapy treatments.

Which platinum complex is used in cancer chemotherapy?

Platinum complexes are used in treating cancer patients by its application in cancer chemotherapy treatment. Cisplatin is the first platinum complex which was observed to have anticancer activity.