What does srb1 do?

The scavenger receptor, class B type 1 (SR-B1), is a multiligand membrane receptor protein that functions as a physiologically relevant high-density lipoprotein (HDL) receptor whose primary role is to mediate selective uptake or influx of HDL-derived cholesteryl esters into cells and tissues.

Where is srb1 located?

Scavenger receptor class B, type I (SR-BI) is an integral membrane protein found in numerous cell types/tissues, including enterocytes, the liver and adrenal gland.

What binds to srb1?

Scavenger receptor B1 (SR-B1) is a protein expressed in liver that binds HDL.

What is the SCARB1 gene?

SCARB1 (Scavenger Receptor Class B Member 1) is a Protein Coding gene. Diseases associated with SCARB1 include High Density Lipoprotein Cholesterol Level Quantitative Trait Locus 6 and Hepatitis C. Among its related pathways are Plasma lipoprotein assembly, remodeling, and clearance and Metabolism of steroids.

What is the role of CD36?

CD36 is a scavenger receptor that functions in high affinity tissue uptake of long chain fatty acids (FA) and contributes under excessive fat supply to lipid accumulation and metabolic dysfunction.

What is LCAT biochemistry?

The LCAT gene provides instructions for making an enzyme called lecithin-cholesterol acyltransferase (LCAT). This enzyme plays a role in removing cholesterol from the blood and tissues.

Where is CD36 located?

CD36 is found on platelets, erythrocytes, monocytes, differentiated adipocytes, skeletal muscle, mammary epithelial cells, spleen cells and some skin microdermal endothelial cells.

What is CD36 biology?

CD36 is a membrane glycoprotein present on platelets, mononuclear phagocytes, adipocytes, hepatocytes, myocytes, and some epithelia. On microvascular endothelial cells, CD36 is a receptor for thrombospondin-1 and related proteins and functions as a negative regulator of angiogenesis.

What is LCAT and its importance?