What does atypical cells mean in thyroid biopsy?
What does atypical cells mean in thyroid biopsy?
ACUS is an abbreviation for “atypical cells of undetermined significance”. This occurs when the thyroid FNA findings don’t show for sure if the nodule is either benign or malignant. The pathologist looks at the cells and just can’t be sure if it is cancer, or non-cancer (benign).
What is atypia of thyroid?
Atypia of undetermined significance/follicular lesions of undetermined significance (AUS/FLUS) refers to an intermediate histologic category of thyroid nodules in The Bethesda System for Reporting Thyroid Cytopathology.
Is atypia of undetermined significance cancer?
Background: Atypia/follicular lesion of undetermined significance (AUS/FLUS) carries a malignancy risk reaching up to 50%. Based on the reported malignancy rate in a given population, the clinical practice towards such a category varies.
What does it mean when a thyroid biopsy comes back suspicious?
“Suspicious” thyroid biopsy: this happens usually when the diagnosis is a follicular or hurtle cell caused lesion. Follicular and hurtle cells are normal cells found in the thyroid. Current analysis of thyroid biopsy results cannot differentiate between follicular or hurtle cell cancer from noncancerous adenomas.
What does atypia mean?
(ay-TIH-pee-uh) State of being not typical or normal. In medicine, atypia is an abnormality in cells in tissue.
What is atypia?
What percent of thyroid biopsies are cancerous?
Overall, about 5–10% of thyroid FNAs will have malignant cytology, 10–25% will be indeterminate or suspicious for cancer, and 60–70% will be benign (5, 6). Patients with nodules that are malignant or suspicious for cancer by FNA usually undergo thyroid surgery.
What percentage of highly suspicious thyroid nodules are cancerous?
Thyroid nodules are common, but only 4–7% of nodules are cancerous. Both ultrasound and fine-needle biopsy have been used to determine if thyroid nodules are cancerous. Fine needle biopsy is considered an accurate method for identifying thyroid cancer, but all nodules do not need to be biopsied.
