Is EBV linear?
Is EBV linear?
Epstein-Barr virus (EBV) is known to be linear in viral particles but EBV circularizes into an episomal form after infection. Recently, the presence of integrated EBV DNA has been reported.
What kind of genome does EBV have?
The EBV genome is composed of linear double-stranded DNA, approximately 172 kilobase pairs (kb) in length. EBV has a series of 0.5 kb terminal direct repeats (TRs) and internal repeat sequences (IRs) that divide the genome into short and long, largely unique sequence domains (Fig.
Is EBV single or double stranded?
The EBV genome is a linear, double-stranded, ~172-kb DNA molecule that encodes > 85 genes (Fig. 1.1).
Is Epstein-Barr virus single stranded?
The EBV is a ubiquitous virus with a 170 kilobase double-stranded DNA genome. In stably infected host cells, the EBV episomes exist in the nuclei of infected host cells as extrachromosomal DNA wrapped with histones.
What are the characteristics of the Epstein-Barr virus?
CHARACTERISTICS: Epstein-Barr virus belongs to genus lymphocryptovirus of the subfamily Gammaherpesvirinae in the Herpesviridae family(1,2). It consists of a double-stranded 172 Kb DNA genome, enclosed within an icosahedral capsid, surrounded by a phospholipid rich envelope(1,3).
Is Epstein-Barr virus enveloped?
Double-stranded linear DNA, 120-150 nm diameter, enveloped, icosahedral; types A and B; Herpesviridae (Gammaherpesvirinae).
How many types of EBV are there?
It has long been known that there are two different EBV genotypes: Type 1 and Type 2, also known as Type A and B, respectively (32).
Is Epstein-Barr virus lytic or lysogenic?
Epstein-Barr virus, which mainly infects B cells and epithelial cells, has two modes of infection: latent and lytic. Epstein-Barr virus infection is predominantly latent; however, lytic infection is detected in healthy seropositive individuals and becomes more prominent in certain pathological conditions.
Is mono and Epstein-Barr the same?
Infectious mononucleosis, also called “mono,” is a contagious disease. Epstein-Barr virus (EBV) is the most common cause of infectious mononucleosis, but other viruses can also cause this disease. It is common among teenagers and young adults, especially college students.
