Does proton pump inhibitors cause dementia?
Does proton pump inhibitors cause dementia?
Recent clinical studies have shown that proton pump inhibitors (PPIs) are associated with risk of dementia, including AD. However, a recent case-control study reported decreased risk of dementia.
Does long term use of omeprazole cause dementia?
The most common PPIs in use were omeprazole (Prilosec), pantoprazole (Protonix), and esomeprazole (Nexium). All participants were free of dementia at the study’s beginning. Yet, after the eight-year follow-up, chronic PPI users had a 44% increased risk of dementia compared with those who did not take any medication.
Do antacids cause dementia?
Study: Long term use of antacids could lead to increased risk for dementia. A recently published study shows that using antacids for a long duration may increase the risk of developing dementia.
Is there a link between pantoprazole and dementia?
PPIs (omeprazole, lansoprazole, esomeprazole, pantoprazole, and others) help reduce the amount of stomach acid made by glands in the lining of the stomach. Research published online on February 15 in JAMA Neurology showed that there may be an association between chronic use of PPIs and an increased risk of dementia.
Do proton pump inhibitors affect memory?
Memory impairment related ADRs found that PPIs users were at increased risk of dementia (Hazard Ratio (HR) 1.38, 95% CI, [1.04–1.83]) and AD (HR, 1.44, 95% CI, [1.01, 2.06]) compared to non-users19.
Which acid reflux medicine causes dementia?
Routine use of proton-pump inhibitors (PPIs)—drugs such as Nexium and Prilosec, used to treat heartburn, gastroesophageal reflux disease or peptic ulcers—may cause or accelerate dementia in elderly individuals.
Does omeprazole affect your memory?
For instance, omeprazole led to deterioration of visual and episodic memory, motor and mental response speed, new learning, short-term and sustained attention, retention and manipulation of visuospatial information, and strategy development [12].
Is there an alternative to PPI medication?
These include proton pump inhibitors such as esomeprazole (Nexium), omeprazole (Prilosec), pantoprazole (Protonix) and lansoprazole (Prevacid). The others are antacids such as Maalox, Mylanta and Tums; and H2 (histamine) receptor antagonists such as famotidine (Pepcid), and cimetidine (Tagamet).
What can I use instead of a PPI?
Although PPIs were found to be more effective in treating symptoms and complications associated with GERD, H2 blockers have proven to be just as effective in suppressing gastric acid. H2 blockers are available by prescription or over-the-counter, and include ranitidine, famotidine, cimetidine and nizatidine.
Can omeprazole cause confusion?
Confusion, agitation, aggression, depression, and hallucinations occurred predominantly in severely ill or elderly patients.
