What does Micropapillary mean in breast cancer?

Micropapillary breast cancer (or invasive micropapillary carcinoma IMPC) is a type of otherwise ‘typical’ invasive ductal carcinoma which exhibits a unique and characteristic growth pattern. This type of breast cancer is quite rare. Only 6% of breast cancer cases are micropapillary.

What is Micropapillary DCIS?

Pathologically, micropapillary DCIS is characterized by the presence of dilated ducts lined by a population of monotonous cells with small finger-like or club-shaped papillary fronds extending into the ductal lumen. The protuberances may form arches, which when present is a distinctive feature.

What are Micropapillary features?

Micropapillary tumors may display clusters of cells that fill the alveolar spaces and are detached from the lining of the alveolar wall, giving the appearance of free-floating cells. From: Tumors and Tumor-Like Conditions of the Lung and Pleura, 2010.

Is invasive ductal breast cancer curable?

Invasive ductal carcinoma is quite curable, especially when detected and treated early.

What is invasive ductal carcinoma with mucinous features?

Mucinous breast cancer, also called colloid breast cancer, is a rare type of invasive ductal breast cancer that accounts for less than 2% of all breast cancers. Like other types of invasive ductal cancer, mucinous breast cancer begins in the milk duct of the breast before spreading to the tissues around the duct.

What is the Nottingham score?

The Nottingham histologic score (or histologic grade) is simply a scoring system to assess the “grade” of breast cancers. The grade is a way to rate how aggressive a tumor may behave.

What stage is DCIS with Microinvasion?

DCIS further develops into invasive ductal carcinoma (IDC) once the tumor breaks through the basement membrane. DCIS with microinvasion (DCIS-MI) is the interim stage between DCIS and IDC. DCIS-MI comprises approximately 1% of all cases of breast cancer, and its morbidity is increasing globally.

What stage is invasive ductal carcinoma?

Generally, the stage of invasive ductal carcinoma is described as a number on a scale of I through IV. Stages I, II, and III describe early-stage cancers, and stage IV describes cancers that have spread outside the breast to other parts of the body, such as the bones or liver.

What are the grades of DCIS?

DCIS is traditionally graded as low, intermediate and high grade, and this is the recommendation made by the last edition of the European Guidelines [3]. There are cases, which are textbook examples of low grade (Fig.

What is the prognosis for invasive mucinous carcinoma?

Overall, patients with mucinous carcinoma have an excellent prognosis, with better than 80% 10-year survival. Similarly, tubular carcinoma has a low incidence of lymph node involvement and a very high overall survival rate.