What is mepacrine used for?

Mepacrine (also known as quinacrine and atabrine) is an acridine derivative initially used in the therapy and prevention of malaria and later as an antiprotozoal and immunomodulatory agent.

Why is quinacrine banned?

There are significant safety concerns regarding the increased risk of reproductive tract malignancies with intrauterine use of quinacrine hydrochloride.

Is mepacrine a quinine?

Scientists at Bayer in Germany first synthesised mepacrine in 1931. The product was one of the first synthetic substitutes for quinine although later superseded by chloroquine.

Can a pregnant woman take mepacrine tablet?

It is contraindicated in pregnant females (crosses the placenta and reaches fetus) and in individuals with impaired hepatic functions. Quinacrine is rapidly absorbed from the gastrointestinal tract and is commercially available in formulations for oral administration (tablets).

How do you take Mepacrine?

Adult: As hydrochloride: 100 mg instilled once a day for 3-4 consecutive days. Adult: As hydrochloride: 100 mg tid for 5-7 days. Child: As hydrochloride: 2 mg/kg tid for 5-7 days. Max dose: 300 mg daily.

What will happen if I stop taking my lupus medication?

Stopping treatment can reduce those side effects, but may trigger a flare-up of lupus symptoms, such as fatigue, rashes, painful and swollen joints, and fever.

Is Mepacrine available in India?

The generic Mepacrine is manufactured by one company. Medindia’s drug directory has currently 3 Brands of Mepacrine listed. New generics and brands are constantly being updated as and when they are approved by drug controller and available in the pharmacies.

Is quinacrine available in India?

The notification bans quinacrine in pellet form for use as a contraceptive, Anyone violating the provision of the Act would be punishable with imprisonment for a term, which may extend to three years or a fine up to Rs 5,000 or both, say health ministry officials.

How do you take mepacrine?

What are the common side effects of quinapril?

Quinapril may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • dizziness.
  • excessive tiredness.
  • cough.
  • upset stomach.
  • vomiting.

Can children take Mepacrine?

Adult: As hydrochloride: 100 mg tid for 5-7 days. Child: As hydrochloride: 2 mg/kg tid for 5-7 days. Max dose: 300 mg daily. Adult: As hydrochloride: 100 mg once a day for the first 1-2 mth.