How do you calculate the anion gap?

Calculation relies on measuring specific cations, Na+ and K+ and specific anions, Cl- and HCO3-. The equation is as follows: (Na+ + K+) – (Cl- + HCO3-) = Anion Gap.

What is the normal range for anion gap?

Normal results are 3 to 10 mEq/L, although the normal level may vary from lab to lab. If your results are higher, it may mean that you have metabolic acidosis.

How is DKA gap calculated?

Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State The anion gap is calculated by subtracting the serum concentrations of chloride and bicarbonate from the sodium concentration.

Do you calculate anion gap with potassium?

Often the potassium is not included in the anion gap calculation, like this: Angion Gap = Na – Cl – C02 = 12.

How is albumin anion gap calculated?

Some authors have proposed that the corrected anion gap (cAG)—anion gap corrected for albumin—be used in all critically ill patients. The cAG as proposed by Figge et al is calculated as follows: cAG (mmol/l) = anion gap + 0.25 × (normal albumin − measured albumin) (albumin is measured in g/l) [Equation 2].

Do you use corrected sodium to calculate anion gap?

Should the corrected sodium be used for calculating the anion gap? No! The anion gap reflects the balance between positively and negatively charged electrolytes in the extracellular fluid. Glucose is electrically neutral and does not directly alter the anion gap.

How do you calculate anion gap without bicarbonate?

Generally considered to be >12 ± 2 mEq/L or mmol/L and reflect the anions that are not included in the formula (albumin, phosphate, sulfate)….Formulas Used:

  1. Anion Gap (without K) = Na – (Cl + HCO3)
  2. Anion Gap (with K) = (Na + K) – (Cl + HCO3)
  3. Delta Gap (without K) = [Na – (Cl + HCO3)] – 12.

What anion gap is DKA?

In mild DKA, anion gap is greater than 10 and in moderate or severe DKA the anion gap is greater than 12. These figures differentiate DKA from HHS where blood glucose is greater than 600 mg/dL but pH is greater than 7.3 and serum bicarbonate greater than 15 mEq/L.

Can you calculate anion gap with CO2?

For practical purposes anion gap is calculated using only Sodium, Chlorides and Total CO2. ((140-(104+24)) = 12.

Do you correct anion gap for albumin?

Conclusions: The observed anion gap can be adjusted for the effect of abnormal serum albumin concentrations as follows: adjusted anion gap = observed anion gap + 0.25 x ([normal albumin] [observed albumin]), where albumin concentrations are in g/L; if given in g/dL, the factor is 2.5.

Can you calculate anion gap with co2?

https://www.youtube.com/watch?v=Ei_Pi_wMi84