How is Otezla dosed?

Following the 5-day titration, the recommended maintenance dosage is 30 mg twice daily taken orally starting on Day 6. This titration is intended to reduce the gastrointestinal symptoms associated with initial therapy. OTEZLA can be administered without regard to meals. Do not crush, split, or chew the tablets.

Can you take 30 mg of Otezla?

The recommended dose of Otezla is 30 mg twice a day after the titration phase is complete – one 30 mg dose in the morning and one 30 mg dose in the evening, approximately 12 hours apart, with or without food. This is a total daily dose of 60 mg.

How much Otezla can you take in a day?

Otezla is available as an oral tablet. The standard recommended dosage is 30 mg twice per day, but treatment is usually started with low doses to reduce the risk of side effects.

How do you use the Otezla starter pack?

How to use Otezla Tablet, Dose Pack. Take this medication by mouth with or without food as directed by your doctor, usually twice daily. The manufacturer directs not to crush, split, or chew the tablet before taking it. However, many similar drugs (immediate-release tablets) can be crushed, split, or chewed.

Can you take 60 mg of Otezla at once?

The recommended dose of Otezla is 30 mg twice a day. The recommended dose of Otezla in severe renal impairment is 30 mg once a day.

Can I cut Otezla in half?

Do not crush, split, or chew Otezla, swallow the tablets whole. Otezla may be taken with or without food. If you develop severe diarrhea, nausea, or vomiting, tell your doctor immediately. Side effects of severe diarrhea or vomiting typically improve quickly with dose reduction or discontinuation of Otezla.

How many tablets are in the Otezla starter pack?

Otezla Starter Pack (14-day or 28-day) 1. If the individual requires additional induction dosing, as verified by the absence of claims for Otezla in the past 130 days, approve a one-time override for one 14-day Starter Pack (27 tablets) or one 28-day Starter Pack (55 tablets).

Can you take 60mg Otezla at once?

The recommended dose of Otezla is 30 mg twice a day. The recommended dose of Otezla in severe renal impairment is 30 mg once a day. To reduce the risk of gastrointestinal symptoms, titrate to recommended dose of 30 mg twice daily according to the following schedule: Day 1: 10 mg in the morning.

What happens if you take 2 Otezla?

If you take too much Otezla, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away. If Otezla is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur.

Does Otezla affect sleep?

Although it isn’t common, Otezla can cause insomnia. Insomnia refers to trouble falling asleep or trouble staying asleep. This side effect is usually mild. For most people, insomnia tends to go away within about 2 weeks after starting Otezla, as your body gets used to the medication.

Can I take Otezla on an empty stomach?

Otezla is an oral medication, meaning it’s taken by mouth every day, once in the morning, and once at night. For example, you can take Otezla with breakfast and dinner each day, or after you brush your teeth in the morning and at night. You can take Otezla with or without food. Do not crush, split, or chew the pill.

How many days is the Otezla starter pack?

When you first start Otezla, your doctor will give you a 14-day Starter Pack. All of the instructions are printed on the pack. During the first 5 days you gradually increase your dose until you reach the 30 mg twice a day. People with severe kidney disease will follow a different schedule for increasing their dose.