Is the Avise test accurate?

The Avise Lupus test had excellent performance characteristics, as compared to the physician’s diagnosis, with sensitivity of 83.3%, specificity of 86.4%, positive predictive value of 87.0%, and negative predictive value of 82.6% (positive likelihood ratio: 6.125 and negative likelihood ratio: 0.19).

What is included in the Avise test?

What assays are included in AVISE CTD:

  • Lupus – SLE Associated Analytes. ANA test by IFA & ELISA.
  • CB-CAP – EC4d.
  • CB-CAP – BC4d.
  • Extractable Nuclear Antigen Antibodies (ENA)
  • Rheumatoid Arthritis (RA)
  • Antiphospholipid syndrome (APS)
  • Thyroid Panel.

Does Avise test for fibromyalgia?

The AVISE Connective Tissue Disease (CTD) test uses autoantibody, erythrocyte-bound C4d (EC4d) and B-cell-bound C4d (BC4d) levels to aid in diagnoses of SLE, other CTDs and fibromyalgia.

What autoimmune diseases does Avise test for?

AVISE® CTD is a blood test that can help doctors diagnose lupus and other autoimmune diseases — like rheumatoid arthritis, Sjögren’s syndrome, or scleroderma.

How do I get my Avise test results?

How to get an AVISE Test:

  1. Step 1: Download the letter for your physician and bring it to your next appointment. Download Letter.
  2. Step 2: Your doctor orders the test.
  3. Step 3: Test results will be sent to your physician within 5 business days.

What does a positive chromatin antibody mean?

Antibodies to chromatin (DNA complexed with histone proteins) are found in >50% of patients with systemic lupus erythematosus (SLE), and are significantly associated with kidney disease in this patient group. Chromatin antibodies may be found in patients with drug-induced lupus.

Is Avise FDA approved?

AVISE tests were developed and performance characteristics determined by Exagen Diagnostics, Inc. While some components of AVISE tests are FDA approved devices, the integrative tests methods have not been cleared or approved by the FDA. Exagen is regulated under CLIA as qualified to perform high complexity testing.