Does sodium thiosulfate lower calcium?

5,14 Sodium thiosulfate inhibits calcium salt precipitation and dissolves calcium deposits. 12,13 It does not have any effects on levels of calcium, phosphorus or PTH. The recommended dose is 20g I.V., three times a week during a minimum of 6 months.

Does sodium thiosulfate cure calciphylaxis?

Sodium thiosulfate (STS) is known as an antidote in cyanide intoxication and has recently been used for treating calciphylaxis.

How do you administer sodium thiosulfate for calciphylaxis?

A multimodality approach using sodium thiosulfate, cinacalcet, and sevelamer has also been used. Sodium thiosulfate has been administered intravenously, intralesionally, or topically; intraperitoneal administration is not recommended owing to the risk of chemical peritonitis.

Why is sodium thiosulfate given during dialysis?

Administration of intravenous sodium thiosulphate (STS) has been purposed to treat CUA in dialysis patients. Due to the poor tolerability of STS, characterized by nausea, hypocalcaemia, metabolic acidosis and QT-interval prolongation, its intralesional administration has been reported.

What are the side effects of sodium thiosulfate?

Side Effects

  • Agitation.
  • hallucinations (seeing, hearing, or feeling things that are not there)
  • mental changes.
  • muscle cramps.
  • nausea and vomiting.
  • pain in the joints.
  • ringing in the ears.

What is sodium thiosulfate solution used for?

SODIUM THIOSULFATE (SOE dee um thi oh SUHL feyt) is used to treat cyanide poisoning. If a poisoning or overdose occurs, get emergency help. Do not treat a poisoning or overdose yourself. It is also a protective medicine used to prevent or lessen the kidney damage that can be caused by cisplatin chemotherapy.

What is the side effects of sodium thiosulfate?

What is the best treatment for calciphylaxis?

Taking medications. A medication called sodium thiosulfate can decrease calcium buildup in the arterioles. It’s given intravenously three times a week, usually during dialysis. Your doctor may also recommend a medication called cinacalcet (Sensipar), which can help control parathyroid hormone (PTH).

How fast do you give sodium thiosulfate?

Adults and teenagers—The usual dose is 12.5 grams injected into a vein at a rate of 0.625 to 1.25 grams (2.5 to 5 milliliters [mL]) per minute.

When do you administer sodium thiosulfate?

Sodium Nitrite Injection and Sodium Thiosulfate Injection are administered by slow intravenous injection. They should be given as early as possible after a diagnosis of acute life-threatening cyanide poisoning has been established.

What is the purpose of sodium thiosulfate?

Sodium thiosulfate, also spelled sodium thiosulphate, is used as a medication to treat cyanide poisoning, pityriasis versicolor, and to decrease side effects from cisplatin. For cyanide poisoning it is often used after the medication sodium nitrite and typically only recommended for severe cases.

How long is sodium thiosulfate good for?

Sodium Thiosulfate (Stabilized) Digital Titrator Cartridge, 2.26 N (Product # 2686901) has a shelf life of 18 months from the date of manufacture and must be stored at 10 – 25 °C.