What happens if you take too much colchicine?

Symptoms of taking too much colchicine can include: feeling or being sick (nausea or vomiting) stomach ache. bloody diarrhoea.

Which drug can cause colchicine levels to go too high?

Antibiotics, such as clarithromycin or telithromycin. Using these drugs with colchicine can result in very high levels of colchicine in your body. This raises your risk of side effects, such as severe muscle damage.

What kind of drug is colchicine?

Colchicine is in a class of medications called anti-gout agents. It works by stopping the natural processes that cause swelling and other symptoms of gout and FMF.

Can colchicine be abused?

There have been no reports of tolerance, dependence, or abuse associated with colchicine use. Colcrys is a brand name of colchicine.

Can colchicine be lethal?

Although the lethal dose of colchicine is considered to be 0.8 mg/kg, patient fatalities have been reported from lower doses, following an acute disease course.

Is colchicine still on the market?

Although the FDA-mandated exclusivity of colchicine ended and generics were introduced to the market, prices have remained high, according to research published in JAMA Internal Medicine. Source: Adobe Stock.

Is colchicine still available?

Colcrys (colchicine) is used for the prevention and treatment of gout flares in adults. Colchicine was previously available as an inexpensive generic, unapproved by the FDA, but became patented as brand-name Colcrys in 2009. Now, finally, a generic is available again, which may mean prices will start to come back down.

How much colchicine is an overdose?

Is colchicine a high risk medication?

Colchicine is a plant-based alkaloid, extracted from Colchicum autumnale (autumn crocus, meadow saffron) and Gloriosa superba (glory lily) used to treat gout and some other inflammatory conditions. It is considered a high-risk medicine because it is associated with significant toxicity when not used correctly.

Is colchicine a hazardous drug?

Colchicine is a pale yellow, nearly odorless powder which darkens on exposure to light. It is used as a medication in the treatment of gout and in research. * Colchicine is on the Hazardous Substance List because it is cited by EPA.