Which is better morphine or pethidine?

Morphine is a more effective and better tolerated analgesic than pethidine in the management of postoperative pain in opioid-dependent patients.

What is the side effect of pethidine?

Like other opioids, pethidine is associated with several side effects, including nausea, vomiting, dizziness, drowsiness and confusion. One study found that when compared to tramadol, pethidine caused more nausea, vomiting and drowsiness in full-term parturients.

Why is Demerol contraindicated sickle cell?

Neurotoxic concerns prompted many hospitals to remove meperidine from their formulary or ban its use in sickle cell disease pain, allowing morphine to emerge as a gold standard analgesic.

Which is stronger pethidine or tramadol?

Conclusions. Tramadol provided adequate analgesia and it was more effective than pethidine to at least six hours for the studied animals. At the higher dose (4 mg/kg) tramadol is probably more effective, since rescue analgesia was not necessary.

How does pethidine make you feel?

it can make you feel woozy, sick and forgetful. if pethidine or diamorphine are given too close to the time of delivery, they may affect the baby’s breathing – if this happens, another medicine to reverse the effect will be given.

How strong is pethidine?

Pethidine is given as an injection (standard dose is 100mg), together with an anti-emetic (anti-sickness) agent, into your upper thigh area by your midwife.

Why is Benadryl given in sickle cell?

Histaminergic effect of opioids It is for this reason that antihistamines are usually given as adjuvants to opioids in treating sickle cell pain. The antihistamines most commonly used as adjuvants include hydroxyzine (Vistaril) and diphen-hydramine (Benadryl).

Can pethidine be given orally?

Pethidine Tablets given orally are indicated for the relief of most types of moderate to severe pain. As it has some antispasmodic activity, it may be the analgesic of choice in renal colic, biliary colic and acute pancreatitis.

Is pethidine stronger than tramadol?

The results of the present study indicated that administration of 100 mg i.m. pethidine was more effective in pain relief at 30 and 60 min after administration when compared with 100 mg tramadol.

How long does pethidine last for?

Pethidine injections in labour It takes about 20 minutes to work after the injection. The effects last between 2 and 4 hours, so would not be recommended if you’re getting close to the pushing (second) stage of labour.