Which form of alpha-lipoic acid is best?

Which form of alpha-lipoic acid is best?

A liquid formulation of R-lipoic acid was found to be better absorbed and more stable in the plasma, suggesting that it might be more efficacious than the solid form in the management of a condition like diabetic neuropathy (9, 10). There may also be differences in bioavailability of the two isomers of lipoic acid.

How much alpha-lipoic acid should you take a day?

Dosing. Alpha-lipoic acid has most often been used by adults in doses of 600-1800 mg by mouth daily for up to 6 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.

Do doctors recommend alpha-lipoic acid?

Research suggests that ALA may help with weight loss, diabetes, memory loss, and some other health conditions. However, there is not enough research to understand its full benefits or effectiveness in humans. ALA is generally safe for adults, but it is best to speak with a doctor before taking any new supplements.

How is alpha-lipoic acid best absorbed?

Studies show that about 30% to 40% of the oral dose of an ALA supplement is absorbed. ALA may be better absorbed if it is taken on an empty stomach.

Are all alpha-lipoic acid the same?

Alpha lipoic acid consists of two different forms (isomers) that have vastly different properties. The “R” form is the biologically active component (native to the body) that is responsible for lipoic acid’s phenomenal antioxidant effect.

Is 600mg of alpha-lipoic acid safe?

Alpha-lipoic supplements are best taken on an empty stomach, as certain foods can lower the acid’s bioavailability (40). Though there is no set dosage, most evidence suggests that 300–600 mg is sufficient and safe.

Which is better R or S alpha-lipoic acid?

The “R” form is the biologically active component (native to the body) that is responsible for lipoic acid’s phenomenal antioxidant effect. The “S” form is produced from chemical manufacture and is not very biologically active. Alpha lipoic acid supplements consist of the “R” and “S” form in a 50/50 ratio.