How do you administer IV penicillin G?

Because of its short half-life, Penicillin G is administered in divided doses, usually every 4–6 hours with the exception of meningococcal meningitis/septicemia, i.e., every 2 hours. 12 to 24 million units/day depending on the infection and its severity administered in equally divided doses every 4–6 hours.

Can penicillin G be given IV?

Penicillin G benzathine and penicillin G procaine injection should never be given intravenously (into a vein), because this may cause serious or life-threatening side effects or death.

How is penicillin G supplied?

Buffered Penicillin G Potassium for Injection, USP may be given intramuscularly or by continuous intravenous drip for dosages of 500,000, 1,000,000, or 5,000,000 units. It is also suitable for intrapleural, intraarticular, and other local instillations.

How do you reconstitute penicillin G potassium?

Penicillin G potassium is highly water soluble. It may be dissolved in small amounts of Water for Injection, or Sterile Isotonic Sodium Chloride Solution for Parenteral Use. All solutions should be stored in a refrigerator.

Is penicillin G narrow spectrum?

Penicillin G and V Penicillin G and penicillin V (phenoxymethylpenicillin) are “natural” penicillins, with a narrow-spectrum of activity due to the development of penicillinases (β-lactamases active against penicillins).

What is the difference between penicillin V and penicillin G?

Penicillin G is a natural penicillin that is produced directly from fermentation of Penicillium crysogenum. Penicillin V is a derivative of penicillin G and because of similarities in spectrum of activity, is considered a natural penicillin.

What happens if penicillin is injected into a vein?

Penicillin G benzathine injection should never be given intravenously (into a vein) because this may cause serious or life-threatening side effects or death.

What class is penicillin G?

Penicillin G injection is in a class of medications called penicillins. It works by killing bacteria that cause infections.

Does penicillin G need to be refrigerated?

This medication should be stored in the fridge but can be kept at room temperature for 7 days.

How much potassium is in penicillin G potassium?

Penicillin G Potassium Injection, USP contains 1.7 mEq potassium and 1.02 mEq of sodium per million units.

What is the meaning of G in penicillin G?

Please. penicillin G the most widely used penicillin, used principally in the treatment of infections due to gram-positive organisms, gram-negative cocci, Treponema pallidum and Actinomyces israelii. The usual forms are salts such as penicillin benzathine, potassium, procaine, or sodium. Called also benzylpenicillin.