How do you test for Henoch-Schönlein purpura?

HSP is usually diagnosed based on the typical skin, joint, and kidney findings.

  1. Throat culture, urinalysis, and blood tests for inflammation and kidney function are used to suggest the diagnosis.
  2. A biopsy of the skin, and less commonly kidneys, can be used to demonstrate vasculitis.

What are HSP guidelines?

Key points

  • Urinalysis and blood pressure measurement must be done when Henoch-Schönlein purpura (HSP) is suspected.
  • Most cases are self-limiting and only require symptomatic management.
  • Close follow-up is critical to identify significant renal involvement requiring intervention. Renal involvement is usually asymptomatic.

Is Henoch-Schönlein purpura same as IgA nephropathy?

Henoch-Schönlein purpura nephritis (HSPN) and IgA nephropathy (IgAN) are considered to be related diseases since both can be encountered consecutively in the same patient, they have been described in twins, and bear identical pathological and biological abnormalities.

Is Henoch-Schönlein purpura palpable?

The classic presentation of Henoch-Schönlein purpura includes palpable purpura, gastrointestinal complaints, arthralgias, and renal involvement. Patients may present with the following: Rash. Joint pain.

How is purpura diagnosed?

Your healthcare provider may recommend tests such as a complete blood count (CBC) or a skin biopsy to determine the cause of the purpura. Determining if the purpura is related to a blood clotting disorder or platelet issue is the first step in diagnosing the condition causing purpura.

Which laboratory examination is fit for HSP?

There is not a specific blood test to diagnose HSP. An abdominal ultrasound may be done in patients with severe abdominal pain. In patients who have partial or unusual symptoms, a biopsy of the skin or the kidney may help make the diagnosis.

Is HSP nephrotic or nephritic?

HSP is an acute small-vessel vasculitis, characterized clinically by a nonthrombocytopenic purpuric rash, nondeforming arthritis, gastrointestinal involvement, and nephritis.

What causes purpura in Henoch-Schonlein?

Nearly half the people who have Henoch-Schonlein purpura developed it after an upper respiratory infection, such as a cold. Other triggers include chickenpox, strep throat, measles, hepatitis, certain medications, food, insect bites and exposure to cold weather.

Is Henoch Schonlein nephritic or nephrotic?

Abstract. Nephritis develops in 18-81% of Henoch-Schönlein purpura patients, and the long-term outcomes of this nephritis show great variation. A nephrotic state at disease onset has been proposed as a predictor of poor renal outcomes.

How does HSP affect the kidneys?

In about half of children with HSP, the kidneys are affected. The tiny blood vessels in the kidneys, which filter blood to remove extra water, salt and waste into the urine, become inflamed. This causes the kidneys to ‘leak’ blood cells and proteins into urine. This is sometimes called HSP nephritis.

What causes Henoch-Schonlein purpura?

Is HSP IgA nephropathy?

Henoch–Schönlein purpura (HSP) is a small vessel systemic vasculitis characterized by small blood vessel deposition of IgA that predominantly affects the skin, joints, gut, and kidney, with nephritis that may be histologically indistinguishable from IgA nephropathy.