Is Cymbalta worse than Zoloft?

Some studies have shown that Zoloft was more effective for symptoms relating to anxiety, agitation, and excessive fear of having an illness. But Cymbalta was more effective for treating physical symptoms, slowed movement/thinking, and sexual problems.

How is Cymbalta different from Zoloft?

Zoloft and Cymbalta belong to different classes of antidepressants. Zoloft is a selective serotonin reuptake inhibitor (SSRI) and Cymbalta is a selective serotonin and norepinephrine reuptake inhibitor (SNRI).

What are the side effects of generic Cymbalta?

Nausea, dry mouth, constipation, loss of appetite, tiredness, drowsiness, or increased sweating may occur. If any of these effects last or get worse, tell your doctor promptly. Dizziness or lightheadedness may occur, especially when you first start or increase your dose of this drug.

How is Cymbalta different from other antidepressants?

While both Cymbalta and Lexapro treat depression and anxiety, they are not the same. Cymbalta blocks the reuptake of both serotonin and norepinephrine in the neuronal synapse, while Lexapro blocks serotonin reuptake only. Cymbalta carries additional indications for pain disorders.

Can Cymbalta replace Zoloft?

Cymbalta and Zoloft are each approved to treat major depressive disorder, but each drug has unique indications as well. Cymbalta is approved to treat generalized anxiety disorder….Conditions treated by Cymbalta and Zoloft.

Condition Cymbalta Zoloft
Stress urinary incontinence Off-label No
Social anxiety disorder No Yes

What drug is better than Cymbalta?

What is a good alternative to Cymbalta? Cymbalta is a selective serotonin and norepinephrine reuptake inhibitor (SNRI). Other SNRIs include Effexor (venlafaxine), Pristiq (desvenlafaxine), and Savella (milnacipran). Talk to a healthcare provider about potential antidepressant treatment options for you.

Is Cymbalta brand better than generic?

The Food and Drug Administration sees no difference between brand-name and generic medications for depression. Most psychiatrists readily prescribe generics as effective copies of the original. That said, it is not at all rare for patients who switch to a generic from a brand-name medication to experience a difference.

What are the worst side effects of duloxetine?

Common Cymbalta side effects include nausea, headache and insomnia. While rare, some serious documented side effects are bleeding of the gastrointestinal tract, liver damage and suicidal ideation. Long lasting withdrawal symptoms have been reported when patients stopped taking Cymbalta.

Is Generic Cymbalta the same as brand?

Cymbalta is available as a generic drug called duloxetine. A generic drug is an exact copy of the active drug in a brand-name medication. The generic is considered to be as safe and effective as the original drug. Generics tend to cost less than brand-name drugs.

Which is better duloxetine or Zoloft?

A study published in 2016 directly compared Cymbalta and Zoloft on their efficacy in treating depression, and the study looked at specific symptoms of depression. Overall, both drugs were shown to be effective at treating depression, with one not being significantly better than the other overall.

How do I switch from sertraline to duloxetine?

Switch medication from sertraline to duloxetine. Before day 1: Gradually reduce dosage of sertraline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.