Is dapagliflozin approved by the FDA?

Today, the U.S. Food and Drug Administration approved Farxiga (dapagliflozin) oral tablets to reduce the risk of kidney function decline, kidney failure, cardiovascular death and hospitalization for heart failure in adults with chronic kidney disease who are at risk of disease progression.

When was Farxiga approved by FDA?

In October 2019 the US FDA approved FARXIGA to reduce the risk of hospitalization for HF in adult patients with T2D and established CV disease or multiple CV risk factors. The approval was based on the DECLARE-TIMI 58 trial.

What is the new drug for heart failure?

Today, the U.S. Food and Drug Administration approved Jardiance (empagliflozin) to reduce the risk of cardiovascular death and hospitalization for heart failure in adults.

What drugs improve ejection fraction?

ACE inhibitors, ARBs or ARNI

  • These medicines include angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor-neprilysin inhibitors (ARNI), and angiotensin II receptor blockers (ARB).
  • They are used to help lower blood pressure, improve blood flow and decrease the strain on your heart.

What is the brand name for dapagliflozin?

Dapagliflozin, sold under the brand names Farxiga (US) and Forxiga (EU) among others, is a medication used to treat type 2 diabetes. It is also used to treat adults with certain kinds of heart failure and chronic kidney disease.

Is Farxiga same as metformin?

By inhibiting the action of SGLT2, Farxiga blocks the reabsorption of glucose by the kidneys, promoting a loss of glucose in the urine and lowering blood glucose levels. Metformin works by decreasing the amount of glucose made by the liver and by improving insulin sensitivity in the liver, muscle, and fat cells.

Is Farxiga safe for kidneys?

Farxiga can cause dehydration (low fluid level), which may lead to kidney damage. If you already have kidney problems, you could be at higher risk of these side effects. Farxiga could also make your kidney problems worse. If your kidney function worsens during treatment, you may need to stop taking Farxiga.

Can heart failure improve?

Heart failure is a chronic disease needing lifelong management. However, with treatment, signs and symptoms of heart failure can improve, and the heart sometimes becomes stronger. Doctors sometimes can correct heart failure by treating the underlying cause.

What is the best heart medication?

The Big 6 Heart Medications

  • Statins — to lower LDL cholesterol.
  • Aspirin — to prevent blood clots.
  • Clopidogrel — to prevent blood clots.
  • Warfarin — to prevent blood clots.
  • Beta-blockers — to treat heart attack and heart failure and sometimes used to lower blood pressure.

How can I increase my ejection fraction naturally?

How to improve your ejection fraction

  1. Partner up with a doctor. Whether it’s a cardiologist or your primary care physician, talk to a doctor about your symptoms.
  2. Be a heart detective. Put this on your doctor’s to-do list, too.
  3. Get moving.
  4. Watch your weight.
  5. Go on a salt strike.
  6. Just say no.
  7. Say goodbye to stress.