Is livial a safe HRT?

Recent research suggests that HRT and Livial slightly increases the risk of having a stroke. The increased risk is seen mainly in women over 60 years old. Other things that can increase the risk of stroke include: Getting older.

Does livial cause weight gain?

Overall tibolone was well tolerated and climacteric symptoms were relieved within 3-5 weeks. The major side effect was weight gain and/or a tendency to bloating and oedema which occurred in 11.28% of our women.

Why is tibolone discontinued in the US?

TUESDAY, Feb. 17, 2009 (HealthDay News) — A large study of tibolone, a drug used to treat menopausal symptoms and to prevent osteoporosis, was halted early after researchers found that the synthetic steroid significantly increased the risk of recurrent breast cancer among survivors of the disease.

Is livial safe?

There have been reports and studies of an increased cell growth or cancer of the lining of the womb in women using Livial. The risk of cancer of the lining of the womb increases with the duration of use. You may have irregular bleeding or drops of blood (spotting) during the first 3-6 months of taking Livial.

Which is better tibolone or HRT?

Tibolone was generally well-tolerated and the overall continuation rate was significantly higher. It seems that tibolone can be an appropriate choice for HRT due to lower rates of bleeding/ spotting episodes and higher acceptance rate in postmenopausal women.

Is tibolone any good?

Moderate-quality evidence suggests that tibolone is more effective than placebo but less effective than HT in reducing menopausal vasomotor symptoms, and that tibolone is associated with a higher rate of unscheduled bleeding than placebo but with a lower rate than HT.

How quickly does livial work?

It usually takes a few weeks before you will feel the initial benefits of HRT and up to three months to feel the full effects. It may also take your body time to get used to HRT. When treatment begins you may experience side effects such as breast tenderness, nausea and leg cramps.

What are the side effects of livial?

Common side effects observed in clinical studies (occurring in 1-10% of the women using Livial) were:

  • vaginal bleeding or spotting.
  • abdominal pain.
  • weight gain.
  • breast pain.
  • unnatural hair growth.
  • vaginal symptoms, such as discharge, itching, and irritation.

What is Livial made from?

Livial tablets contain the active ingredient tibolone, which is a synthetic steroid medicine used for hormone replacement therapy (HRT).

Can tibolone cause stroke?

Stroke. The LIFT study identified a significantly (2ยท2-times) increased risk of stroke, mostly ischaemic, in tibolone users; risk increased from the first year of treatment. Baseline risk of stroke is strongly age-dependent, and so the absolute risk with tibolone increases with older age.

Is tibolone good HRT?

Moderate-quality evidence suggests that tibolone is more effective than placebo and less effective than combined hormone therapy (HT) in reducing vasomotor symptoms in postmenopausal women.

Does tibolone help anxiety?

In our study, we found that tibolone was superior to placebo in anxiety and Kupperman index scores. In menopausal women, the psychological benefits of HT may occur because of the relief of vasomotor symptoms and a reduction in vaginal dryness, and this is known as the ‘domino effect’ (2).