Can plasmacytoma spread?

Most cases of plasmacytomas cause paraproteinemia. Metastatic spread of plasmacytoma occurs to soft tissues frequently and occasionally to bones. Plasmacytoma is treated with surgery, radiotherapy, and chemotherapy as required.

Does plasmacytoma turn into multiple myeloma?

Solitary plasmacytoma of the bone can sometimes be cured with radiation therapy or surgery to destroy or remove the tumor. However, 70 percent of people with solitary plasmacytoma eventually develop multiple myeloma.

Is plasmacytoma considered multiple myeloma?

Multiple myeloma is not confined to a specific bone or location within a bone. It tends to involve the entire skeleton. When only one lesion is found it is called a plasmacytoma. Most doctors believe that plasmacytoma is simply an early, isolated form of multiple myeloma.

How common is plasmacytoma?

Solitary bone plasmacytomas are uncommon and make up approximately 5% of all of the plasma cell disorders. Solitary extramedullary plasmacytomas are even less common. Solitary plasmacytomas occur more commonly in men than women.

What causes plasmacytoma cancer?

At present, there is no known cause of solitary plasmacytoma. However, some evidence indicates that factors such as genetics, viral infections, and inhaled irritants may contribute. Potential risk factors for the condition include older age, being male, and being African American.

How long does it take plasmacytoma to turn into multiple myeloma?

Solitary bone plasmacytoma (SBP) progresses to multiple myeloma at a rate of 65-84% at 10 years and 65-100% at 15 years. The median onset of conversion to multiple myeloma is 2-5 years with a 10-year disease-free survival rate of 15-46%. The overall median survival time is 10 years.

Does a plasmacytoma hurt?

Symptoms. Spinal plasmacytomas may cause dull, aching pain as they destroy normal bone. If a vertebra is sufficiently weakened by the plasmacytoma, a painful compression fracture may result.