What is Charcot-Marie-Tooth disease Type 2?

CHARCOT-MARIE-TOOTH disease (CMT) type 2 or hereditary motor and sensory neuropathy type 2 is a genetically heterogeneous group of axonal neuropathies with motor and sensory abnormalities and signs of axonal degeneration on electrodiagnostic investigation and in sural nerve biopsy specimens.

What is HMSN?

Hereditary motor sensory neuropathy (HMSN), also known as Charcot-Marie-Tooth Disease, is an inherited, progressive disease of the nerves with weakness and numbness more pronounced in the legs than the arms.

Is Charcot-Marie-Tooth a developmental disability?

Charcot-Marie-Tooth disease-deafness-intellectual disability syndrome is a rare demyelinating hereditary motor and sensory neuropathy characterized by early-onset, slowly progressive, distal muscular weakness and atrophy with no sensory impairment, congenital sensorineural deafness and mild intellectual disability ( …

Can Charcot-Marie-Tooth be cured?

There’s no cure for Charcot-Marie-Tooth disease (CMT), but therapies are available to help reduce your symptoms and enable you to live as independently as possible. As CMT gets worse over time, you’ll need to be assessed regularly to check for any changes in your condition.

Can neuropathy be inherited?

Hereditary neuropathies are passed on genetically from parent to child. They’re sometimes called inherited neuropathies. Neuropathies can also be nonhereditary, or acquired. Acquired neuropathies are caused by other conditions, such as diabetes, thyroid disease, or alcohol use disorder.

Is autonomic neuropathy a genetic disorder?

Hereditary sensory and autonomic neuropathy type II (HSAN2) is a rare genetic disorder that usually begins in childhood, affecting the nerves that serve the lower legs and feet and the lower arms and hands.

Does massage help CMT?

Conclusion: Massage therapy may positively affect pain intensity and ROM associated with CMT. Future studies linking massage therapy and CMT are needed.