What class of antiarrhythmic drug is amiodarone?

Amiodarone is a class III antiarrhythmic, based on the benzofuran structure used in atrial and ventricular fibrillation therapy 12. Amiodarone is a multichannel blocker affecting delayed rectifier IKr, sodium channel and L‐type calcium currents.

Is amiodarone an antiarrhythmic drug?

However, its pronounced antiarrhythmic effects redirected its use and amiodarone has become a widely used class III anti-arrhythmic drug. Compared to other antiarrhythmic drugs, it is more effective in treating both supraventricular and ventricular arrhythmias.

How does amiodarone work as an antiarrhythmic?

Amiodarone is a class III antiarrhythmic that blocks potassium channels. In acute therapy, most of its effects are due to its action as a sodium channel blocker, thereby reducing automaticity and conduction velocity in the ventricles.

Is amiodarone an inotropic drug?

In conclusion, amiodarone exerts acute electrophysiological and inotropic effects in vitro. The class III antiarrhythmic action of amiodarone is linked with positive inotropy.

What is the action of amiodarone?

It is used to restore normal heart rhythm and maintain a regular, steady heartbeat. Amiodarone is known as an anti-arrhythmic drug. It works by blocking certain electrical signals in the heart that can cause an irregular heartbeat.

What is the primary action of amiodarone?

Amiodarone has multiple effects on myocardial depolarization and repolarization that make it an extremely effective antiarrhythmic drug. Its primary effect is to block the potassium channels, but it can also block sodium and calcium channels and the beta and alpha adrenergic receptors.

Is amiodarone the best antiarrhythmic?

Amiodarone, dofetilide, dronedarone, and sotalol are class III agents, potassium channel blockers that lead to prolongation of QT interval and possible ventricular arrhythmias or torsades de pointes. Amiodarone is considered the most potent antiarrhythmic agent.

How does amiodarone work?

What is the classification of amiodarone?

Amiodarone belongs to the group of medicines known as antiarrhythmics. It works directly on the heart tissue and will slow the nerve impulses in the heart. This helps keep your heart rhythm normal. This medicine is available only with your doctor’s prescription.

Is amiodarone used for rate or rhythm control?

Amiodarone is the drug recommended for rate control of AF with rapid ventricular response in patients with chronic heart failure in whom beta-blockers cannot be administered. Amiodarone shows little negative inotropic effect and can be used in patients with reduced left ventricular function.